Guard Column Starter Set, Phenyl Hydride 2.o, complete with 5 each 2.0 mm ID x 10 mm long cartridges packed with 2.2 um, 120 A phase and 1 each guard column holder. Cogent TYPE-C Brand. 1 EA.
Additional Info:
The 69220‑PG1 Phenyl Hydride 2.o Guard Column Starter Set provides everything required to implement Cogent TYPE‑C™ guard column protection for high‑efficiency Phenyl Hydride 2.o analytical methods. This complete starter kit is designed to protect analytical columns from particulates, strongly retained contaminants, and irreversible matrix buildup, helping maintain chromatographic performance and extend column lifetime in high‑pressure workflows.
This starter set includes a stainless‑steel guard cartridge column holder suitable for high‑pressure operation and five Phenyl Hydride 2.o guard cartridges packed with 2.2 µm, 120 Å Phenyl Hydride 2.o stationary phase.
Guard Column Use Case: Phenyl Hydride 2.o Protection for High‑Pressure Methods
Guard columns act as a sacrificial protection stage installed upstream of the analytical column. When using Phenyl Hydride 2.o chemistry, particularly in HILIC‑mode and high‑pressure analytical workflows, guard columns help:
Protect analytical columns from particulate contamination
Trap strongly retained or irreversible sample components
Preserve selectivity, peak shape, and retention reproducibility
Extend the usable lifetime of high‑efficiency analytical columns
The Phenyl Hydride 2.o guard format is especially valuable for small‑particle methods, where contamination can quickly impact performance.
What’s Included in the Starter Set
This guard column starter kit includes:
1 stainless‑steel guard cartridge column holder designed for high‑pressure use
5 Phenyl Hydride 2.o guard cartridges, each 2.0 mm ID × 10 mm length, packed with 2.2 µm, 120 Å Phenyl Hydride 2.o phase
Based on average analytical use, the five included cartridges typically provide sufficient protection for the lifetime of one analytical column.
Each guard cartridge is shipped in an individual, closeable Delrin® storage case to prevent drying, contamination, or handling damage prior to installation.
Phenyl Hydride 2.o Stationary Phase Consistency
The guard cartridges in this kit are packed with the same Phenyl Hydride 2.o chemistry used in corresponding analytical columns, ensuring:
No change in chromatographic selectivity or elution order
Minimal added dead volume
Seamless integration into existing Phenyl Hydride 2.o HILIC methods
Stable performance under high‑organic mobile‑phase conditions
Phase consistency is critical for maintaining method integrity when guard protection is implemented.
Compatibility & Recommended Use
Designed for 2.1 mm ID analytical Phenyl Hydride 2.o columns
Compatible with Cogent TYPE‑C™ analytical columns
Suitable for HILIC‑mode analytical HPLC workflows
Requires the included Cogent TYPE‑C™ guard column holder
Operational Notes
Guard cartridges are easily replaced without removing the analytical column
Replacement frequency depends on sample cleanliness and matrix complexity
Guard use is strongly recommended for LC‑MS, biological, and complex sample applications, especially with 2.2 µm particle columns