Guard Column cartridges, Phenyl Hydride 2.o, replacement, 2.0 mm ID x 10 mm long cartridges packed with 2.2 um, 120 A phase. Cogent TYPE-C Brand. 5/PK.

Additional Info:

The 69220‑PG2 Phenyl Hydride 2.o Guard Column Replacement Cartridges provide reliable, sacrificial protection for analytical Phenyl Hydride 2.o HPLC columns in high‑pressure, high‑efficiency workflows. Each cartridge is packed with 2.2 µm, 120 Å Phenyl Hydride 2.o stationary phase on Cogent TYPE‑C™ silica hydride, designed to capture particulates and strongly retained contaminants before they reach the analytical column.

These replacement cartridges help preserve peak shape, retention stability, and column efficiency, extending analytical column lifetime and maintaining consistent performance.

A compatible guard column holder is required and is sold separately.

Guard Column Use Case: Phenyl Hydride 2.o Protection for Analytical Methods

Guard cartridges act as a sacrificial protection stage installed upstream of the analytical column. When using Phenyl Hydride 2.o chemistry, particularly in HILIC‑mode and LC‑MS workflows, guard columns help:

  • Protect analytical columns from particulate contamination

  • Trap strongly retained or irreversible sample components

  • Preserve chromatographic selectivity and reproducibility

  • Extend the usable lifetime of high‑efficiency analytical columns

The 5‑pack configuration is ideal for laboratories running routine analytical methods and requiring predictable guard‑replacement availability.

Phenyl Hydride 2.o Stationary Phase Consistency

These guard cartridges are packed with the same Phenyl Hydride 2.o chemistry used in corresponding analytical columns, ensuring:

  • No change in chromatographic selectivity or elution order

  • Minimal added dead volume

  • Seamless integration into existing Phenyl Hydride 2.o HILIC methods

  • Stable performance under high‑organic mobile‑phase conditions

Maintaining phase consistency is essential for method integrity when guard protection is applied.

Construction, Handling, and Packaging

Each 69220‑PG2 guard cartridge features:

  • 2.0 mm ID × 10 mm length

  • Stainless‑steel tube with stainless‑steel frits

  • Clear labeling for identification and traceability

To prevent drying, contamination, or handling damage, each cartridge is shipped individually in a black Delrin® storage case.

Compatibility & Recommended Use

  • Designed for 2.1 mm ID analytical Phenyl Hydride 2.o columns

  • Suitable for HILIC‑mode analytical HPLC workflows

  • Compatible with Cogent TYPE‑C™ guard column holders (sold separately)

Operational Notes

  • Guard cartridges can be replaced easily without removing the analytical column

  • Replacement frequency depends on sample cleanliness and matrix complexity

  • Guard use is strongly recommended for LC‑MS, biological, and complex sample applications, especially with 2.2 µm particle columns

 

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