Guard Column cartridge, Phenyl Hydride 2.o, replacement, 2.0 mm ID x 10 mm long cartridge packed with 2.2 um, 120 A phase. Cogent TYPE-C Brand. 1 EA.

Additional Info:

The 69220‑PG3 Phenyl Hydride 2.o Guard Column Replacement Cartridge provides targeted, sacrificial protection for analytical Phenyl Hydride 2.o HPLC columns when a single‑unit replacement is preferred. Packed with 2.2 µm, 120 Å Phenyl Hydride 2.o stationary phase on Cogent TYPE‑C™ silica hydride, this guard cartridge helps preserve peak shape, retention stability, and column efficiency by capturing particulates and strongly retained contaminants before they reach the analytical column.

A compatible guard column holder is required and is sold separately. The cartridge installs directly upstream of the analytical column.

Guard Column Use Case: Single‑Cartridge Flexibility for Phenyl Hydride 2.o Methods

Single guard cartridges are ideal when flexibility is required in high‑pressure HILIC‑mode analytical workflows, or when replacing guard protection on an as‑needed basis. The 69220‑PG3 is commonly selected when:

  • Occasional replacement is preferred over purchasing multi‑packs

  • Different methods require different guard‑phase configurations

  • Evaluating guard usage prior to committing to a 5‑pack

The guard cartridge functions as a sacrificial protection stage, helping maintain analytical column integrity while reducing downtime and replacement costs.

Phenyl Hydride 2.o Stationary Phase Consistency

This guard cartridge is packed with the same Phenyl Hydride 2.o chemistry used in corresponding analytical columns, ensuring:

  • No change in chromatographic selectivity or elution order

  • Minimal added dead volume

  • Seamless integration into existing Phenyl Hydride 2.o HILIC methods

  • Stable performance under high‑organic mobile‑phase conditions

Maintaining phase consistency is essential to preserve method integrity when implementing guard protection.

Construction, Handling, and Packaging

Each 69220‑PG3 guard cartridge features:

  • 2.0 mm ID × 10 mm length

  • Stainless‑steel tube with stainless‑steel frits

  • Clear labeling for identification and traceability

To prevent drying, contamination, or handling damage, each cartridge is shipped in an individual, black Delrin® storage case.

Compatibility & Recommended Use

  • Designed for use with 2.1 mm ID analytical Phenyl Hydride 2.o columns

  • Suitable for HILIC‑mode analytical HPLC workflows

  • Compatible with Cogent TYPE‑C™ guard column holders (sold separately)

Operational Notes

  • Guard cartridges can be replaced quickly without removing the analytical column

  • Replacement frequency depends on sample cleanliness and matrix complexity

  • Guard use is strongly recommended for LC‑MS, biological, and complex sample applications, particularly with 2.2 µm particle columns

 

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