Guard Column cartridges, Silica-C 2.o, replacement, 2.0 mm ID x 10 mm long cartridges packed with 2.2 um, 120 A phase. Cogent TYPE-C Brand. 5/PK.
Additional Info:
The 40200‑PG2 Silica‑C™ 2.o Guard Column Replacement Cartridges provide high‑pressure, sacrificial protection for Silica‑C™ 2.o analytical HPLC columns used in HILIC and normal‑phase workflows. Packed with 2.2 µm, 120 Å Silica‑C™ 2.o stationary phase on Cogent TYPE‑C™ silica hydride, these guard cartridges are designed to capture particulates and strongly retained contaminants before they reach the analytical column.
Routine replacement of guard cartridges helps maintain chromatographic selectivity, peak shape, and retention stability, while extending analytical column lifetime—particularly important for small‑particle, high‑pressure methods.
A compatible TYPE‑C™ guard column holder is required and is sold separately.
Guard Column Use Case: Silica‑C™ 2.o Protection for High‑Pressure Analytical Methods
Guard columns act as a sacrificial protection stage installed upstream of the analytical column. When running Silica‑C™ 2.o (2.2 µm) chemistry, guard cartridges help:
Protect analytical columns from particulate contamination
Trap strongly retained or irreversible sample components
Preserve chromatographic reproducibility and selectivity
Extend analytical column lifetime and reduce replacement costs
The 5‑pack configuration is ideal for laboratories running routine high‑pressure analytical methods that require predictable guard‑replacement cycles.
Cartridge Construction & Packaging
Each 40200‑PG2 guard cartridge features:
2.0 mm ID × 10 mm length
Stainless‑steel tube with stainless‑steel frits
Clear labeling for identification and traceability
To prevent drying, contamination, or handling damage, each cartridge is shipped individually in a black Delrin® storage case.
Phase Consistency: Silica‑C™ 2.o TYPE‑C™ Chemistry
These replacement cartridges are packed with the same Silica‑C™ 2.o TYPE‑C™ silica hydride chemistry used in corresponding analytical columns, ensuring:
No change in chromatographic selectivity or elution order
Minimal added dead volume
Seamless integration into existing Silica‑C™ 2.o methods
Stable performance under HILIC and normal‑phase conditions
Maintaining phase consistency is critical to preserving method integrity in high‑pressure workflows.
Compatibility & Recommended Use
Designed for 2.1 mm ID analytical HPLC columns
Compatible with Cogent TYPE‑C™ guard column holders
Suitable for HILIC and normal‑phase analytical workflows using Silica‑C™ 2.o chemistry
These cartridges are intended as replacement consumables for laboratories already using TYPE‑C™ guard systems with small‑particle analytical columns.
Operational Notes
Guard cartridges can be replaced quickly without removing the analytical column
Replacement frequency depends on sample cleanliness and matrix complexity
Guard usage is strongly recommended for LC‑MS, biological, and complex sample matrices, especially with 2.2 µm particle columns