Metal Content Affects Silica Particle and Contributes to Peak Shape - Tech Information
April 22, 2012
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Date: 22-APRIL-2012 Last Updated: 1-DECEMBER-2025
The electron withdrawing properties of trace metals in standard HPLC silica particles enhances the negativity of surface silanol groups and contributes to peak tailing when high levels of trace metals are present.
NOTE: This much less of a concern for TYPE-C™ silica.
The electron withdrawing properties of trace metals in standard HPLC silica particles enhances the negativity of surface silanol groups and contributes to peak tailing when high levels of trace metals are present.
NOTE: This much less of a concern for TYPE-C™ silica.