Mobile Phase Delivery Bottle Cap and O-Ring Specifications - Tech Information
April 4, 2013
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Date: 04-APRIL-2013   Last Updated: 19-AUGUST-2026
 

Overview

Mobile phase delivery systems rely on properly designed bottle closures to help maintain solvent purity, minimize contamination, and provide secure tubing connections. The cap assembly and O-ring materials must be compatible with common chromatography solvents while providing a reliable seal throughout routine laboratory use.

These components are designed for use with standard GL 45 threaded laboratory bottles commonly used for mobile phase storage and solvent delivery.


Bottle Cap Construction

The mobile phase delivery bottle caps are manufactured from:

  • Polypropylene (PP) cap body
  • PTFE insert

This combination provides:

  • Broad chemical compatibility
  • Durability in laboratory environments
  • Compatibility with common HPLC solvents
  • Reliable sealing performance

The PTFE insert helps provide a chemically resistant contact surface for demanding chromatography applications.
 


O-Ring Construction

The O-rings supplied with the mobile phase delivery system are manufactured from:

  • EPDM (Ethylene Propylene Diene Monomer)
  • FEP exterior coating

The combination of an EPDM core and FEP outer layer provides:

  • Chemical resistance
  • Flexibility
  • Sealing reliability
  • Compatibility with a wide range of aqueous and organic solvent systems

This construction helps protect the elastomer while maintaining sealing performance.


GL 45 Bottle Compatibility

The caps, inserts, and O-rings are designed for use with:

GL 45 threaded bottles

This thread standard is widely used in chromatography laboratories for:

  • Mobile phase reservoirs
  • Solvent storage bottles
  • HPLC bottle systems
  • Laboratory reagent containers

Proper thread compatibility helps ensure secure installation and leak-free operation.


O-Ring Dimensions

Approximate O-ring dimensions are:

  • Outside Diameter -  36.4 mm
  • Inside Diameter -  28.6 mm

These dimensions are intended to provide proper sealing performance when installed in compatible GL 45 bottle cap assemblies.


Typical Applications

Mobile phase delivery bottle cap systems are commonly used for:

  • HPLC solvent delivery
  • UHPLC solvent reservoirs
  • Mobile phase preparation
  • LC-MS solvent systems
  • Laboratory reagent transfer
  • Chromatography support operations

Proper cap and O-ring selection helps support consistent solvent handling and system reliability.


Key Takeaways

  • Mobile phase delivery caps are manufactured from polypropylene with PTFE inserts.
  • O-rings utilize an EPDM core with an FEP coating.
  • Components are designed for GL 45 threaded bottles.
  • O-rings have an approximate OD of 36.4 mm and ID of 28.6 mm.
  • Material selection provides chemical compatibility for chromatography applications.
  • The system is intended for mobile phase storage and solvent delivery operations.


​Additional Resources

For mobile phase bottle caps, solvent reservoir accessories, GL 45 closure systems, product images, and ordering information, view: Mobile Phase Delivery Bottle Caps, GL 45 Reservoir Accessories, Product Images, and Ordering Information


 

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