Headspace Septa Temperature Performance Specifications - HPLC Primer
December 29, 2014
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Date:  29-DECEMBER-2014  Last Updated: 27-OCTOBER-2025

The table below outlines the recommended operational temperature ranges for various Headspace cap septa materials. These specifications are intended to guide optimal performance in Headspace GC applications.

⚠️ Note: These values represent the recommended temperature limits for septa materials only. They do not indicate the overall safety limits of the complete Headspace system (including vial, cap, septa, and gas composition).

Material Recommended Temperature Range (°C)
Silicone/PTFE (fully laminated)       -60 to 200
Butyl/PTFE (fully laminated)       -40 to 120
Butyl      -40 to 120
Pharma-Fix (Butyl/PTFE)      -40 to 120
Silicone/Aluminum Foil      -60 to 220

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