Can the BASIK™ Filter Degasser Remove CO₂?

Yes.

The BASIK™ Filter Degasser is designed to combine:

• Solvent filtration
• Mobile phase degassing

During vacuum filtration, dissolved gases such as: Carbon dioxide (CO₂) and  Oxygen (O₂)  can be removed from the solvent along with entrained air bubbles.

This helps prepare mobile phases for HPLC and UHPLC applications where dissolved gases may contribute to:

• Baseline instability
• Pump cavitation
• Bubble formation
• Flow inconsistencies

How Does the Degassing Process Work?

The BASIK™ Filter Degasser uses vacuum-assisted filtration to:

1. Remove particulate contamination from solvents.
2. Reduce dissolved gases within the mobile phase.
3. Help minimize bubble formation in solvent lines.
4. Improve solvent preparation efficiency.

The combination of filtration and degassing makes the system useful for preparing many common HPLC mobile phases.

Important Considerations

Dissolved Gases Can Return

After degassing, exposure to the atmosphere can allow gases to re-dissolve into the solvent over time.

For best results:

• Use freshly prepared mobile phases when possible.
• Minimize solvent exposure to air.
• Keep bottles properly capped when not in use.

Solvent Compatibility

Not all solvents or chemical solutions are compatible with filter-degasser systems.

Always verify:

• Membrane compatibility
• Solvent compatibility
• Vacuum compatibility

before processing specialty solvents or aggressive chemical solutions.

Benefits of Proper Mobile Phase Degassing

Effective degassing may help:

• Reduce pump cavitation
• Minimize bubbles in solvent lines
• Improve detector stability
• Enhance chromatographic reproducibility
• Improve overall HPLC system performance

Key Takeaways

• The BASIK™ Filter Degasser can help remove dissolved CO₂ from many HPLC solvents.
• Vacuum filtration assists with both particulate removal and solvent degassing.
• Oxygen and other dissolved gases may also be reduced during filtration.
• Gases can re-enter solvents after exposure to air.
• Always verify solvent compatibility before use.