Cogent TYPE‑C™ Silica HPLC columns are engineered to deliver highly stable, low‑noise chromatographic performance, making them an excellent choice for LC‑MS applications where sensitivity and reproducibility are essential.
Exceptional LC‑MS Performance
These columns consistently produce lower background noise in LC‑MS compared to most conventional HPLC columns. This reduction in baseline interference supports improved analyte detection—especially for compounds present at low concentrations.
Reliable Retention Time Precision
For chromatographic precision, Cogent TYPE‑C™ columns typically deliver <1% RSD for retention time across replicate injections. This level of reproducibility ensures stable method performance and dependable results over time.
Enhanced Detection Precision
For the most accurate quantitation in LC‑MS, the use of a suitable internal standard is strongly recommended. Incorporating an internal standard improves detection precision and supports consistent, reliable analyte measurement.
