Amlodipine, Valsartan and Hydrochlorothiazide Tablet USP Assay - AppNote
January 21, 2025
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Date: 21-JANUARY-2025   Last Updated: 30-AUGUST-2026

Alternate L1 Column used for a USP Assay 

This AppNote demonstrates the USP Method for Amlodipine, Valsartan, and Hydrochlorothiazide Tablets working with the Cogent RP C18. As shown in the Chromatograms, the Peak efficiency is superb and USP Peak tailing guidelines are easily met with the Column. This demonstrates a great alternative Column for easy plug and play with this USP Method.
 
 

Method Conditions:
Column: Cogent RP C18™ 3 um, 100A
Catalog No.: 68318-15P
Dimensions: 4.6 mm x 150 mm

Sample Preparation:

-- A: Valsartan/Hydrochlorothiazide standards (0.16/0.025 mg per mL)
-- B: Valsartan/Amlopidine Sample (3.2/0.1 mg per mL)


Note 1: For the full method conditions and details, consult the official United States Pharmacopeia–National Formulary (USP–NF.)
 

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