p-Toluenesulfonic Acid Monohydrate Analyzed with HPLC RP Method- AppNote
November 29, 2021
/
/
/
/
/
/
A Reliable Method for Detection of an Oxonium Salt

This Reproducible Method has been developed for Analysis of p-Toluenesulfonic Acid Monohydrate. The data below, (overlay of 5 chromatograms ) illustrates how the compound can be adequately Retained and detected using a simple Mobile Phase. RSD values ***

 Mass Spec friendly Mobile Phase with Formic Acid as an additive.

5 Injections of p-Toluenesulfonic Acid Monohydrate  

Method Conditions
Column: Cogent RP C18™, 4μm, 100Å
Catalog No.: 68518-25P
Dimensions: 4.6mm x 75mm
Mobile Phase:
Injection vol.: 10uL
Flow rate: 1.0mL / minute
Detection: UV @ 210nm
Sample Preparation: p-Toluenesulfonic Acid Monohydrate prepared as 2.5 mg / mL standard solution in DI Water

Notes : p-Toluenesulfonic Acid Monohydrate is widely used as catalyst agent in the synthesis of pharmaceuticals, pesticides, polymerization stabilizer and organic synthesis (esters, etc.), paint intermediates and resin curing agent. 

This Method was developed by and is presented courtesy of ARL- Eutech Scientific Services.

© Copyright 2026. MICROSOLV. All Rights Reserved. Website & Hosting by BlueTone Media