p-Toluenesulfonic Acid Monohydrate Analyzed with HPLC RP Method - AppNote
November 29, 2021
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Date: 29-NOVEMBER-2021 Last Updated: 21-SEPTEMBER-2026
A Reliable Method for Detection of an Oxonium Salt
This Reproducible Method has been developed for Analysis of p-Toluenesulfonic Acid Monohydrate. The data below, (overlay of 5 chromatograms ) illustrates how the compound can be adequately Retained and detected using a simple Mobile Phase. RSD values *** Mass Spec friendly Mobile Phase with Formic Acid as an additive.
5 Injections of p-Toluenesulfonic Acid Monohydrate
Column: Cogent RP C18™, 4 μm, 100 Å
Catalog No.: 68518-25P
Dimensions: 4.6 x 75 mm
Mobile Phase:
Injection vol.: 10 uL
Flow rate: 1.0 mL/minute
Detection: UV @ 210 nm
Sample Preparation: p-Toluenesulfonic Acid Monohydrate prepared as 2.5 mg/mL standard solution in DI Water
Notes : p-Toluenesulfonic Acid Monohydrate is widely used as catalyst agent in the synthesis of pharmaceuticals, pesticides, polymerization stabilizer and organic synthesis (esters, etc.), paint intermediates and resin curing agent. This Method was developed by and is presented courtesy of ARL- Eutech Scientific Services.
