Catalog Number - 58022-PES13-A

The 58022-PES13-A AQ™ Syringe Filters are pharmaceutical-grade, high-performance membrane filters engineered for HPLC sample preparation, sterile filtration, and dissolution testing in regulated laboratory environments. Featuring a 0.22 µm Polyethersulfone (PES) membrane, these filters deliver exceptional consistency, ultra-low protein binding, and extractable-free performance, ensuring maximum sample purity and reproducible analytical results.

The 13 mm format is optimized for low sample volume applications, making these filters ideal for biological samples, buffers, and protein solutions where sample recovery and conservation are critical.

✅ Critical Compliance Advantage (No Flush Required)

These filters are validated and certified to meet stringent regulatory requirements, including:

• US FDA CFR Title 21, Part 210.3(b)(6) for minimum fiber release

• USP <788> for particulate matter in injectables

• USP requirements for “Sterile Water for Injection”

Because of this validated performance:

• ✅ No initial flushing is required

• ✅ No need to discard the first 200 µL of filtrate

• ✅ Preserves valuable samples—critical for low-volume workflows

• ✅ Eliminates a common cause of failed methods and investigations

👉 This provides a strong operational and compliance advantage for QC/QA and biopharma laboratories, where reproducibility, efficiency, and sample integrity are essential.

Performance & Design

The 0.22 µm PES membrane is optimized for sterile filtration and fine particulate removal, ensuring maximum clarity and protection of analytical systems.

PES membrane chemistry offers ultra-low protein binding, low extractables, and excellent flow rates, making it ideal for protein solutions, buffers, and culture media, where maximum recovery of sensitive analytes is required.

The 13 mm design minimizes hold-up volume, maximizing recovery from small or high-value samples, making it ideal for method development and precision analytical workflows.

The white housing with orange lettering allows rapid identification of 0.22 µm PES filters, and each pack includes a Certificate of Analysis for full traceability and compliance.

Key Features

0.22 µm PES Membrane (Pharma Grade)

• Ideal for sterile filtration and fine particulate removal

• Ensures maximum sample clarity

✅ No Initial Flush Required (Validated)

• Extractable-free from first filtrate

• No 200 µL discard required

Ultra-Low Protein Binding

• Maximizes recovery of proteins and biomolecules

• Ideal for biological and biopharma samples

Optimized for Low Sample Volumes (13 mm)

• Minimizes hold-up volume

• Ideal for limited or high-value samples

High Throughput Performance

• Fast filtration with minimal resistance

• Suitable for analytical workflows

Low Extractables

• Ensures clean chromatography

• Improves reproducibility

Absolute Retention

• Reliable sterile filtration performance

• Suitable for critical analytical methods

Regulatory Compliance

• Meets FDA CFR Title 21 requirements

• Complies with USP <788>

• Suitable for Sterile Water for Injection

Autoclavable & EO Sterilizable

• 121°C for 30 minutes or Ethylene Oxide

Color-Coded (White / Orange)

• Identifies 0.22 µm PES filters

Typical Applications

• HPLC & UHPLC Sample Preparation – fine particulate removal

• Sterile Filtration – bacterial and contaminant removal

• Protein & Biomolecule Filtration – low binding, high recovery

• Cell Culture Media & Buffers – clean and efficient filtration

• Method Development – limited or high-value samples

• Dissolution Testing – pharmaceutical QC workflows

• Regulated Laboratory Methods – validated, compliant processes

Specifications

• Filter Type: Syringe Filter (Pharma Grade)

• Membrane Material: PES (Polyethersulfone)

• Pore Size: 0.22 µm

• Diameter: 13 mm

• Housing Material: Polypropylene (PP)

• Color Code: White / Orange (0.22 µm PES)

• Connection Type: Luer Lock / Slip

• Chemical Compatibility: Aqueous solutions, buffers, biological samples

• Protein Binding: Ultra-low

• Extractables: None detectable (no flush required)

• Sterilization: Autoclave or EO

• Compliance: FDA CFR 21, USP <788>

• Certification: Certificate of Analysis included

• Sterility: Non-sterile

• Pack Size: 50/PK

• Brand: AQ™

Resources & Ordering Options

• Order PES syringe filters, 0.22 µm, 13 mm – 100/pack quantity

• Purchase PES syringe filters, 0.22 µm, 13 mm – 1000/case quantity