Syringe Filters, 25mm, Glassfiber, 0.45um Pore Size. White/Grey Polypropylene, AQ Brand. 1000/CS.

Additional Info:

The 58045-G25-K AQ™ Syringe Filters are pharmaceutical-grade, high-throughput glass microfiber filters designed for HPLC sample preparation, dissolution testing, and bioanalysis in regulated laboratory environments. Featuring a 0.45 µm borosilicate glass fiber membrane, these filters provide high loading capacity, fast flow rates, and reliable filtration of challenging samples.

Glass fiber membranes are ideal for viscous and particulate-heavy samples, offering excellent throughput and broad chemical compatibility with both aqueous buffers and organic solvents.

✅ Critical Compliance Advantage (No Flush Required)

Validated to meet key regulatory standards:

  • US FDA CFR Title 21, Part 210.3(b)(6) – minimum fiber release

  • USP <788> – particulate matter in injectables

  • USP “Sterile Water for Injection”

Benefits:

  • ✅ No initial flushing required

  • ✅ No 200 µL discard required

  • ✅ Extractable-free from first filtrate

  • ✅ Reduces risk of failed methods


Performance & Design

The 0.45 µm pore size is optimized for sample clarification and prefiltration, especially for high-particulate or viscous samples.

The glass fiber membrane provides high dirt-loading capacity, making it ideal as a prefilter before finer membranes or as a standalone solution for difficult samples.

The 25 mm format supports high sample volumes, while the 1000/case packaging is ideal for high-throughput laboratories and production workflows.

The white housing with grey lettering enables quick identification, and each case includes a Certificate of Analysis.


Key Features

0.45 µm Glass Fiber Membrane (Pharma Grade)

  • Ideal for viscous and particulate-heavy samples

  • High loading capacity

✅ No Initial Flush Required (Validated)

  • No 200 µL discard required

Broad Chemical Compatibility

  • Suitable for aqueous and organic solvents

High Throughput (25 mm)

  • Handles larger sample volumes

  • Fast flow performance

Prefiltration Capability

  • Protects downstream membranes

  • Reduces clogging

Bulk Packaging (1000/Case)

  • Reduces cost per analysis

  • Ideal for high-volume labs

Low Extractables

  • Clean analytical results

Regulatory Compliance

  • FDA CFR 21, USP <788>

Color-Coded (White / Grey)

  • Identifies glass fiber filters


Typical Applications

  • HPLC & UHPLC Sample Preparation – particulate-heavy samples

  • Dissolution Testing – complex matrices

  • Bioanalysis – biological sample cleanup

  • Prefiltration – before 0.45 µm or 0.22 µm membranes

  • Environmental & Industrial Samples


Specifications

  • Membrane Material: Borosilicate Glass Fiber

  • Pore Size: 0.45 µm

  • Diameter: 25 mm

  • Housing: Polypropylene (PP)

  • Color Code: White / Grey

  • Chemical Compatibility: Aqueous & organic solvents

  • Extractables: None detectable (no flush required)

  • Sterilization: Autoclave or EO

  • Compliance: FDA CFR 21, USP <788>

  • Pack Size: 1000/Case

  • Brand: AQ™


Resources & Ordering Options

 

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