Syringe Filters, 25mm, Glassfiber, 0.45um Pore Size. White/Grey Polypropylene, AQ Brand. 50/PK.
Additional Info:
The 58045-G25-A AQ™ Syringe Filters are pharmaceutical-grade glass microfiber filters designed for HPLC sample preparation, dissolution testing, and bioanalytical workflows. Featuring a 0.45 µm borosilicate glass fiber membrane, these filters provide high loading capacity, fast flow rates, and reliable filtration of challenging samples.
Glass fiber membranes are ideal for viscous and particulate-heavy samples, offering excellent throughput and broad chemical compatibility with both aqueous buffers and organic solvents.
✅ Critical Compliance Advantage (No Flush Required)
Validated to meet key regulatory standards:
US FDA CFR Title 21, Part 210.3(b)(6) – minimum fiber release
USP <788> – particulate matter in injectables
USP “Sterile Water for Injection”
Benefits:
✅ No initial flushing required
✅ No 200 µL discard required
✅ Extractable-free from first filtrate
✅ Reduces risk of failed methods
Performance & Design
The 0.45 µm pore size is optimized for sample clarification and prefiltration, especially for high-particulate or viscous samples.
The glass fiber membrane provides high dirt-loading capacity, making it ideal as a prefilter before final membrane filtration or as a standalone solution for difficult samples.
The 25 mm format supports high sample volumes and throughput, making it suitable for routine and high-volume laboratory workflows.
The white housing with grey lettering enables quick identification, and each pack includes a Certificate of Analysis.
Key Features
0.45 µm Glass Fiber Membrane (Pharma Grade)
Ideal for viscous and particulate-heavy samples
High loading capacity
✅ No Initial Flush Required (Validated)
No 200 µL discard required
Broad Chemical Compatibility
Suitable for aqueous and organic solvents
High Throughput (25 mm)
Handles larger sample volumes
Fast flow performance
Prefiltration Capability
Protects downstream membranes
Reduces clogging
Low Extractables
Clean analytical results
Regulatory Compliance
FDA CFR 21, USP <788>
Color-Coded (White / Grey)
Identifies glass fiber filters
Typical Applications
HPLC & UHPLC Sample Preparation – particulate-heavy samples
Dissolution Testing – complex matrices
Bioanalysis – protein / biological sample cleanup
Prefiltration – prior to 0.45 µm or 0.22 µm membranes
Environmental & Industrial Samples – high particulate load
Specifications
Membrane Material: Borosilicate Glass Fiber
Pore Size: 0.45 µm
Diameter: 25 mm
Housing: Polypropylene (PP)
Color Code: White / Grey
Chemical Compatibility: Aqueous & organic solvents
Extractables: None detectable (no flush required)
Sterilization: Autoclave or EO
Compliance: FDA CFR 21, USP <788>
Pack Size: 50/PK
Brand: AQ™
Resources & Ordering Options
Purchase glass fiber syringe filters, 0.45 µm, 25 mm – 100/pack quantity
Order glass fiber syringe filters, 0.45 µm, 25 mm – 1000/case quantity