Syringe Filters, 25mm, Nylon, 0.45um Pore Size. Green Polypropylene, AQ Brand. 1000/CS.
Additional Info:
The 58045-N25-K AQ™ Syringe Filters are pharmaceutical-grade, high-throughput membrane filters engineered for HPLC sample preparation and dissolution testing in regulated laboratory environments. Featuring a 0.45 µm Nylon‑66 membrane, these filters deliver exceptional consistency, ultra-low adsorption, and extractable-free performance, ensuring accurate and reproducible analytical results across high-volume workflows.
✅ Critical Compliance Advantage (No Flush Required)
These filters are validated and certified to meet stringent regulatory requirements, including:
US FDA CFR Title 21, Part 210.3(b)(6) for minimum fiber release
USP <788> for particulate matter in injectables
USP requirements for “Sterile Water for Injection”
Because of this validated performance:
✅ No initial flushing is required
✅ No need to discard the first 200 µL of filtrate
✅ Eliminates wasted sample and saves analyst time
✅ Reduces risk of failed methods and costly investigations
👉 This creates a clear operational and compliance advantage for QC/QA laboratories, especially in high-throughput environments where efficiency and documentation are critical.
Performance & Design
The 0.45 µm pore size is optimized for sample clarification and prefiltration, providing high flow rates with minimal clogging, ideal for routine and high-volume analysis.
The advanced 16-channel outlet design reduces back pressure, allowing smooth filtration with less hand force, improving operator comfort and throughput in repetitive workflows.
Nylon‑66 membrane chemistry ensures broad compatibility with aqueous and organic solvents, while maintaining ultra-low adsorption—even for charged analytes, supporting accurate quantitation.
The 25 mm format is designed for high sample throughput, and the green color coding allows rapid identification of 0.45 µm nylon filters.
Each case is supplied with a Certificate of Analysis, ensuring full traceability and regulatory compliance.
Key Features
0.45 µm Nylon‑66 Membrane (Pharma Grade)
Ideal for clarification and prefiltration
High consistency for validated analytical methods
✅ No Initial Flush Required (Validated)
Extractable-free from first filtrate
Eliminates sample waste and variability
Ultra-Low Adsorption
Suitable for charged and sensitive compounds
Maximizes analyte recovery
Advanced 16-Channel Outlet Design
Reduces back pressure
Requires less hand force
Regulatory Compliance
Meets FDA CFR Title 21 requirements
Complies with USP <788>
Suitable for Sterile Water for Injection
Broad Solvent Compatibility
Compatible with aqueous and organic HPLC solvents
Ideal for mixed solvent systems
25 mm Diameter for High Throughput
Handles larger sample volumes
Improves productivity in high-volume labs
Autoclavable & EO Sterilizable
121°C for 30 minutes or Ethylene Oxide
Color-Coded (Green)
Identifies 0.45 µm nylon filters
Bulk Packaging (1000/Case)
Reduces cost per test
Ideal for high-throughput QC environments
Typical Applications
HPLC & UHPLC Sample Preparation – reliable sample clarification prior to injection
Dissolution Testing – pharmaceutical QC and release workflows
Regulated Laboratory Methods – compliant and repeatable processes
Pharmaceutical Analysis – injectables and formulations
Aqueous & Organic Filtration – mixed solvent compatibility
High-Throughput QC Labs – consistent, efficient performance
Specifications
Filter Type: Syringe Filter (Pharma Grade)
Membrane Material: Nylon‑66
Pore Size: 0.45 µm
Diameter: 25 mm
Housing Material: Polypropylene (PP)
Color Code: Green (0.45 µm Nylon)
Connection Type: Luer Lock / Slip
Chemical Compatibility: Aqueous and organic solvents
Extractables: None detectable (no flush required)
Sterilization: Autoclave or EO
Compliance: FDA CFR 21, USP <788>
Certification: Certificate of Analysis included
Sterility: Non-sterile
Pack Size: 1000/Case
Brand: AQ™
Resources & Ordering Options
Order Nylon‑66 syringe filters, 0.45 µm, 25 mm – 100/pack quantity
Purchase Nylon‑66 syringe filters, 0.45 µm, 25 mm – 50/pack quantity