Syringe Filters, 25mm, Regenerated Cellulose (RC), 0.45um Pore Size. Brown Polypropylene, AQ Brand. 50/PK.
Additional Info:
The 58045-R25-A AQ™ Syringe Filters are pharmaceutical-grade regenerated cellulose (RC) membrane filters designed for HPLC sample preparation and dissolution testing in regulated laboratory environments. Featuring a 0.45 µm regenerated cellulose membrane, these filters provide low extractables, excellent recovery, and consistent chromatographic performance.
Regenerated cellulose membranes offer very low protein binding and low hold-up volume, making them ideal for protein solutions, culture media, and buffer filtration, especially when maximum sample recovery is critical.
✅ Critical Compliance Advantage (No Flush Required)
Validated to meet key regulatory standards:
US FDA CFR Title 21, Part 211.92 – minimum fiber release
USP <788> – particulate matter in injectables
USP “Sterile Water for Injection”
Benefits:
✅ No initial flushing required
✅ No 200 µL discard required
✅ Improves recovery and efficiency
✅ Reduces risk of failed methods
Performance & Design
The 0.45 µm pore size is optimized for sample clarification and prefiltration, delivering reliable particulate removal and consistent flow.
The RC membrane provides low protein binding and low adsorption, ensuring high recovery of analytes, particularly for biological samples.
The 25 mm format supports larger sample volumes, making it well suited for routine and high-throughput workflows.
Not recommended for use with strong acids or bases.
The brown housing enables quick identification, and each pack includes a Certificate of Analysis.
Key Features
0.45 µm Regenerated Cellulose Membrane (Pharma Grade)
Very low protein binding
Ideal for biological and aqueous samples
✅ No Initial Flush Required (Validated)
No 200 µL discard required
Low Hold-Up Volume
Maximizes sample recovery
High Throughput (25 mm)
Handles larger sample volumes
Low Extractables
Clean chromatographic results
Biological Compatibility
Suitable for proteins, buffers, culture media
Regulatory Compliance
FDA CFR 21 (211.92), USP <788>
Color-Coded (Brown)
Identifies RC filters
Typical Applications
HPLC & UHPLC Sample Preparation – aqueous sample filtration
Protein & Biomolecule Samples – maximum recovery
Cell Culture Media & Buffers
Dissolution Testing – pharmaceutical QC
Routine Analytical Workflows
Specifications
Membrane Material: Regenerated Cellulose (RC)
Pore Size: 0.45 µm
Diameter: 25 mm
Housing: Polypropylene (PP)
Color Code: Brown
Protein Binding: Very Low
Hydrophilicity: Hydrophilic
Extractables: None detectable (no flush required)
Chemical Compatibility: Aqueous solutions (avoid strong acids/bases)
Sterilization: Autoclave or EO
Compliance: FDA CFR 21, USP <788>
Pack Size: 50/PK
Brand: AQ™
Resources & Ordering Options
Purchase regenerated cellulose syringe filters, 0.45 µm, 25 mm – 100/pack quantity
Order regenerated cellulose syringe filters, 0.45 µm, 25 mm – 1000/case quantity