CUSTOM ITEM: HPLC Column, Silica-C, 4um, 3.0mm ID x 100mm Length, 100A. Cogent TYPE-C Brand. 1 EA. CUSTOM ORDER.
Additional Info:
The 40000‑10P‑3 Silica‑C™ HPLC Column is manufactured using https://www.mtc-usa.com/typec_about, providing distinct selectivity and robust performance for HILIC and normal‑phase separations. Unlike conventional bonded‑silica phases, this unmodified silica hydride surface contains no end‑capping or organic ligands, delivering stable retention behavior and rapid equilibration—especially advantageous in normal‑phase chromatography.
This column is produced as a custom, made‑to‑order item and is optimized for analytes requiring non‑aqueous or minimally aqueous mobile phases, where traditional silica columns may suffer from moisture sensitivity and longer equilibration times.
Application Focus: Silica‑C™ for HILIC & Normal‑Phase Separations
Silica‑C™ stationary phases are selected for compounds that are not soluble in water or require non‑polar solvent systems. The Silica‑C™ phase is particularly effective for:
Lipids
Peptides and proteins
Oligonucleotides
Other analytes requiring non‑polar solvents or normal‑phase conditions
The silica hydride surface supports reproducible retention and improved method stability compared to conventional silica phases.
Key Advantages of Silica‑C™ TYPE‑C™ Technology
Compared to traditional bonded‑silica columns, Silica‑C™ columns offer:
Faster equilibration between injections
No need to control moisture in mobile‑phase solvents
Robust column lifetime under demanding solvent systems
Distinct selectivity, particularly beneficial in normal‑phase workflows
These attributes make Silica‑C™ a reliable solution for consistent, non‑aqueous analytical separations.
Why Choose the 3.0 mm × 100 mm Format
The 3.0 mm ID × 100 mm length configuration provides high‑resolution performance comparable to 4.6 mm ID columns, while delivering meaningful efficiency and cost advantages:
Similar run times to 4.6 mm analytical columns
Reduced mobile‑phase consumption
Lower operating flow rates
Lower backpressure, improving system compatibility
This format is frequently selected for LC‑MS methods where additional resolution is required but solvent usage must be minimized.
Particle Size and Performance
The 4 µm particle size delivers reliable efficiency with manageable backpressure, supporting robust performance on standard analytical HPLC systems while providing meaningful resolution improvements over shorter or wider‑ID formats.
System Requirements and Flow Rates
Typical flow range (3.0 mm ID): ~0.4–0.6 mL/min
System capability: Compatible with standard analytical HPLC systems
Note: No specialized low‑flow or UHPLC‑only equipment is required
Flow‑rate optimization should consider mobile‑phase viscosity, column temperature, and system pressure limits.
Made‑to‑Order Columns & Pricing Information
This is a custom, made‑to‑order column.
Columns are manufactured specifically to order
Orders cannot be canceled once placed
Custom columns are non‑returnable