CUSTOM ITEM: HPLC Column, Bidentate C18, 4um, 3.0mm ID x 50mm Length, 100A. Cogent TYPE-C Brand. 1 EA.
Additional Info:
The 40018‑05P‑3 Cogent Bidentate C18™ HPLC Column is a custom‑manufactured, mid‑bore reversed‑phase column designed to deliver the same chromatographic performance and run times as a 4.6 mm ID column, while using significantly less mobile phase. Built on Cogent TYPE‑C™ silica hydride technology, this column combines unique selectivity, rapid equilibration, and exceptional chemical robustness.
The stationary phase features an aliphatic C18 chain bonded via two direct silicon–carbon bonds (bidentate attachment). This chemistry creates a surface that is highly hydrophobic yet versatile, capable of retaining compounds that often do not retain on traditional C18 columns made with conventional silica. Unlike standard C18 phases, this column can be used with 100 % aqueous mobile phases without phase collapse or analyte loss.
The 3.0 mm internal diameter provides a practical balance between performance and solvent savings. Flow rates are lower than those required for 4.6 mm columns, reducing solvent consumption and waste, yet no special low‑flow hardware is required, making this format easy to adopt on standard analytical HPLC systems.
Why Choose the 3.0 mm ID Bidentate C18™ Format
This column size is ideal for laboratories seeking to reduce solvent usage without sacrificing method comparability. Key advantages include:
Similar run times and resolution to 4.6 mm ID columns
Lower mobile‑phase consumption and operating cost
Reduced waste generation
Compatibility with standard analytical HPLC instrumentation
The 40018‑05P‑3 is especially useful for laboratories transitioning toward more efficient and sustainable analytical workflows.
Key Features
Cogent TYPE‑C™ Silica Hydride Technology
Reduced silanol activity and secondary interactions
Faster equilibration than conventional C18 columns
Extremely robust column lifetimes
Bidentate C18™ Bonding
Two‑point attachment via direct Si–C bonds
Unique selectivity not achievable with standard C18 phases
Retains both strongly hydrophobic and select hydrophilic compounds
Broad Mobile‑Phase Compatibility
Stable with 100 % aqueous mobile phases
Resistant to degradation at very low pH (below 2)
Suitable for aggressive or unconventional methods
Solvent‑Saving Column Geometry
3.0 mm ID × 50 mm length
Comparable performance to 4.6 mm ID columns
Lower flow rates reduce solvent use without specialized equipment
Typical Applications
Routine analytical HPLC
Methods requiring unique reversed‑phase selectivity
Mixed hydrophobic and hydrophilic analytes
Low‑pH separations
Solvent‑reduction initiatives
Method development and method transfer
Made‑to‑Order & Pricing Information
This is a custom, made‑to‑order item.
Orders cannot be canceled once placed
Custom items are non‑returnable