CUSTOM ITEM: HPLC Column, Bidentate C18, 4um, 3.0mm ID x 150mm Length, 100A. Cogent TYPE-C Brand. 1 EA.
Additional Info:
The 40018‑15P‑3 Cogent Bidentate C18™ HPLC Column is a custom‑manufactured, long‑format mid‑bore column designed for analytical separations requiring maximum resolving power while reducing mobile‑phase consumption compared to standard 4.6 mm ID columns. Built on Cogent TYPE‑C™ silica hydride technology, this column offers unique selectivity, rapid equilibration, and exceptional chemical robustness under demanding method conditions.
The stationary phase uses an aliphatic C18 chain bonded via two direct silicon–carbon bonds (bidentate attachment) to a silica hydride surface. This chemistry produces a phase that is highly hydrophobic yet versatile, enabling retention of compounds that often show weak or unstable retention on conventional silica‑based C18 columns. Unlike traditional C18 phases, this column supports 100 % aqueous mobile phases without phase collapse and tolerates very low pH conditions (below pH 2) with no damage.
The 3.0 mm internal diameter and 150 mm length deliver increased plate count and separation efficiency relative to shorter formats, while operating at lower flow rates than 4.6 mm ID columns—providing meaningful solvent savings without requiring specialized low‑flow equipment.
Why Choose the 3.0 × 150 mm Bidentate C18™ Format
This configuration is commonly selected when:
Maximum analytical resolution is required
50 mm or 100 mm columns do not fully resolve critical pairs
Solvent‑use reduction is desired without altering instrumentation
Methods operate at low pH or with aqueous‑dominant mobile phases
The long column length delivers higher peak capacity, while TYPE‑C™ silica hydride chemistry maintains fast equilibration and long service life.
Key Features
Cogent TYPE‑C™ Silica Hydride Technology
Reduced silanol activity and secondary interactions
Faster equilibration than conventional C18 columns
Extremely robust column lifetime
Bidentate C18™ Bonding
Two‑point attachment via direct Si–C bonds
Unique selectivity not achievable with standard C18 phases
Retains strongly hydrophobic and select hydrophilic analytes
Exceptional Method Flexibility
Compatible with 100 % aqueous mobile phases
Stable at very low pH (below 2)
Suitable for aggressive or unconventional reversed‑phase methods
Solvent‑Efficient High‑Resolution Geometry
3.0 mm ID × 150 mm length
Higher resolution vs. 100 mm columns
Lower solvent usage than 4.6 mm ID formats
Compatible with standard analytical HPLC systems
Typical Applications
High‑resolution analytical HPLC
Method development and optimization
Compounds poorly retained on conventional C18 columns
Low‑pH separations
Aqueous‑dominant reversed‑phase methods
Solvent‑reduction initiatives
Custom Order Information
This product is classified as a Custom Item. Custom items are manufactured to order, non‑returnable, and cannot be canceled once production has begun.
Please contact Customer Service for lead time confirmation, documentation, or customization inquiries.