CUSTOM ITEM: HPLC Column, Bidentate C18, 4um, 4.6mm ID x 75mm Length, 100A. Cogent TYPE-C Brand. 1 EA.
Additional Info:
The 40018‑75P Cogent Bidentate C18™ HPLC Column is a custom‑manufactured analytical column designed for applications requiring additional retention and resolving power beyond standard short‑length formats. Constructed using Cogent TYPE‑C™ silica hydride technology, this column delivers unique selectivity, fast equilibration, and exceptional chemical robustness not achievable with conventional silica‑based C18 phases.
The stationary phase consists of an aliphatic C18 chain bonded via two direct silicon–carbon bonds (bidentate attachment) to a silica hydride surface. This design yields a stationary phase that is highly hydrophobic yet unusually versatile, capable of retaining compounds that often show poor retention on traditional C18 columns. The column can be operated with 100 % aqueous mobile phases without phase collapse and can tolerate very low pH conditions (below pH 2) without degradation.
The 75 mm column length provides increased interaction time compared to 50 mm formats, improving separation of closely eluting compounds while maintaining reasonable run times. This makes the column well suited for challenging analytical separations where extended resolution is required.
Why Choose the 75 mm Bidentate C18™ Format
Compared to shorter analytical columns, the 75 mm length offers:
Improved resolution for closely related analytes
Greater method flexibility for gradient optimization
Enhanced selectivity when additional retention is required
Coupled with TYPE‑C™ silica hydride chemistry, this format maintains fast equilibration and long column lifetime even under aggressive method conditions.
Key Features
Cogent TYPE‑C™ Silica Hydride Technology
Non‑traditional reversed‑phase chemistry
Reduced silanol activity and secondary interactions
Faster equilibration than conventional C18 columns
Extremely robust column lifetime
Bidentate C18™ Bonding
Two‑point attachment via direct Si–C bonds
Unique selectivity compared to standard C18 phases
Retains hydrophobic compounds and select hydrophilic analytes
Exceptional Method Flexibility
Compatible with 100 % aqueous mobile phases
Stable at very low pH (below 2)
Suitable for unconventional or aggressive methods
Analytical‑Scale Performance
4.6 mm ID × 75 mm length
Increased resolving power vs. shorter columns
Compatible with standard analytical HPLC systems
Typical Applications
Challenging reversed‑phase separations
Compounds poorly retained on conventional C18 columns
Low‑pH analytical methods
Aqueous‑dominant mobile phases
Method development and optimization
Made‑to‑Order & Pricing Information
This is a custom, made‑to‑order item.
Orders cannot be canceled once placed
Custom items are non‑returnable