Prep HPLC Column, Bidentate C18, 4um, 100A. 30mm ID x 50mm Length. Cogent TYPE-C Brand. 1 EA.
Additional Info:
The 40018‑P30‑50 Cogent Bidentate C18™ Preparative HPLC Column is a short‑length, large‑diameter prep column designed for very high sample loads and rapid purification cycles. Built on Cogent TYPE‑C™ silica hydride technology, this column provides excellent selectivity, fast equilibration, and very robust column lifetime in demanding preparative workflows.
The stationary phase consists of an aliphatic C18 chain bonded via two direct silicon–carbon bonds (bidentate attachment) to a silica hydride surface. This chemistry creates a phase that is highly hydrophobic yet versatile, enabling strong, stable retention of hydrophobic molecules, metabolites, and amine‑containing analytes—including in aqueous‑dominant or low‑pH mobile phases that can degrade or destabilize conventional silica‑based prep C18 materials.
With a 30 mm internal diameter and 50 mm length, this column prioritizes throughput and capacity over extended resolution, making it ideal when large injection volumes must be processed quickly and fractions collected efficiently.
System Note: A specialized preparative HPLC system (high‑flow pump capacity, appropriate tubing/valving, injector, and fraction‑collection hardware) is required for columns of this size.
Why Choose the 30 × 50 mm Prep Bidentate C18™ Format
This configuration is commonly selected when:
Maximum sample loading is required
Rapid purification cycles are prioritized over extended resolving power
Hydrophobic or basic analytes challenge traditional prep C18 phases
Robust, repeatable prep performance is essential
The large diameter supports high throughput, while TYPE‑C™ silica hydride chemistry maintains stability and reproducibility under aggressive preparative conditions.
Key Features
Cogent TYPE‑C™ Silica Hydride Technology
Non‑traditional reversed‑phase chemistry
Faster equilibration than conventional prep C18 columns
Very robust lifetimes for repeated purification cycles
Bidentate C18™ Bonding
Two‑point attachment via direct Si–C bonds
Strong, stable hydrophobic retention
Particularly effective for hydrophobic and amine‑containing analytes
Preparative Geometry for Throughput
30 mm ID × 50 mm length
Extremely high mass loading capability
Short cycle times for efficient fraction collection
Broad Operating Window
Compatible with aqueous‑dominant mobile phases
Stable under low‑pH conditions
Tolerates aggressive purification methods
Typical Applications
Preparative purification with very high sample loads
Rapid fraction collection workflows
Hydrophobic molecule and metabolite purification
Amine‑containing analytes
Scale‑up from analytical or smaller preparative formats
Made‑to‑Order & Pricing Information
This is a custom, made‑to‑order item.
Orders cannot be canceled once placed
Custom items are non‑returnable