Semi Prep HPLC Column, Bidentate C18, 4um, 100A. 10mm ID x 150mm Length. Cogent TYPE-C Brand. 1 EA.
Additional Info:
The 40018‑SP150 Cogent Bidentate C18™ Semi‑Preparative HPLC Column is a long‑format semi‑prep purification column designed for workflows requiring maximum separation and higher purity fractions. Built on Cogent TYPE‑C™ silica hydride technology, this column provides excellent selectivity, fast equilibration, and very robust lifetime under repetitive purification conditions.
The stationary phase employs an aliphatic C18 chain bonded via two direct silicon–carbon bonds (bidentate attachment) to a silica hydride surface. This chemistry produces a phase that is highly hydrophobic yet versatile, enabling strong retention of hydrophobic molecules, metabolites, and amine‑containing analytes while maintaining stability in aqueous‑dominant and low‑pH mobile phases—conditions that often challenge conventional silica‑based prep C18 columns.
With a 10 mm internal diameter and an extended 150 mm length, this column delivers increased plate count and separation efficiency compared with shorter semi‑prep formats, making it ideal when improved resolution between closely eluting components is required prior to fraction collection.
System Note: A specialized semi‑preparative HPLC system (appropriate pump flow capacity, injector, tubing, and fraction‑collection hardware) is required for columns of this size.
Why Choose the 10 × 150 mm Semi‑Prep Bidentate C18™ Format
This configuration is commonly selected when:
Semi‑preparative runs demand maximum resolution and purity
50 mm or 100 mm semi‑prep columns do not provide adequate separation
Larger sample volumes must be purified with tighter fraction cut windows
Hydrophobic or basic analytes challenge traditional prep C18 materials
The longer length increases interaction time and selectivity while preserving the inherent durability and flexibility of TYPE‑C™ silica hydride chemistry.
Key Features
Cogent TYPE‑C™ Silica Hydride Technology
Non‑traditional reversed‑phase chemistry
Faster equilibration than conventional prep C18 columns
Very robust lifetimes for repeated purification cycles
Bidentate C18™ Bonding
Two‑point attachment via direct Si–C bonds
Strong, stable hydrophobic retention
Suitable for hydrophobic and amine‑containing analytes
Semi‑Preparative Geometry for Maximum Resolution
10 mm ID × 150 mm length
Highest plate count among 10 mm semi‑prep options
Supports purification requiring tighter separations
Broad Operating Window
Compatible with aqueous‑dominant mobile phases
Stable under low‑pH conditions
Tolerates aggressive purification methods
Typical Applications
Semi‑preparative purification with high purity targets
Fraction collection of hydrophobic compounds
Metabolite isolation and cleanup
Amine‑containing analytes
Scale‑up from analytical and method refinement
Made‑to‑Order & Pricing Information
This is a custom, made‑to‑order item.
Orders cannot be canceled once placed
Custom items are non‑returnable