CUSTOM ITEM: HPLC Column, Silica-C 2.o, 2.2um, 2.1mm ID x 75mm Length, 120A, High Pressure. Cogent TYPE-C Brand. 1 EA.
Additional Info:
The 40200‑75P‑2 Silica‑C™ 2.o HPLC Column is manufactured using Cogent TYPE‑C™ silica hydride technology, delivering “near‑UHPLC” performance with 2.2 µm particles and 120 Å pore size under high‑pressure analytical conditions. The silica hydride surface provides faster equilibration, improved robustness, and enhanced method stability compared to conventional bonded‑silica phases, particularly in HILIC and normal‑phase separations.
This column is produced as a custom, made‑to‑order item and is optimized for applications requiring non‑aqueous or low‑water mobile phases where traditional silica columns can present equilibration and moisture‑control challenges.
Application Focus: Silica‑C™ for HILIC & Normal‑Phase Separations
Silica‑C™ stationary phases are selected for the analysis of compounds that are not soluble in water or require non‑polar or minimally aqueous mobile phases. The Silica‑C™ 2.o phase is particularly effective for:
Lipids
Peptides and proteins
Oligonucleotides
Other compounds requiring non‑polar solvents or HILIC conditions
The TYPE‑C™ silica hydride surface supports stable retention and reproducible performance without the variability often associated with conventional silica phases.
Key Advantages of Silica‑C™ TYPE‑C™ Technology
Compared to traditional bonded‑silica columns, Silica‑C™ columns provide:
Faster equilibration between injections
No need to control moisture in mobile‑phase solvents
Robust column lifetime under demanding solvent systems
Improved run‑to‑run reproducibility in HILIC and normal‑phase methods
These features make Silica‑C™ a preferred solution when consistent performance is required in non‑aqueous separations.
Why Choose the 2.1 mm × 75 mm Format
The 2.1 mm ID × 75 mm length configuration offers a balance between speed and resolution, providing:
Greater resolving power than 50 mm formats
Shorter run times than longer analytical columns
Reduced solvent consumption compared to larger‑diameter columns
Improved compatibility with LC‑MS workflows due to lower flow rates
This intermediate length is useful when additional resolution is required without a significant increase in analysis time.
Particle Size and Efficiency
The 2.2 µm particle size delivers high efficiency and narrow peak widths under high‑pressure operation, providing near‑UHPLC performance while remaining compatible with many modern analytical HPLC systems.
System Requirements and Flow Rates
Typical flow range (2.1 mm ID): ~0.2–0.3 mL/min
System capability: Requires an HPLC system capable of accurate, stable low‑flow delivery
Important note: Not all standard HPLC systems are suitable for reliable operation at these reduced flow rates
Flow‑rate optimization should consider mobile‑phase viscosity, column temperature, and system pressure limits.
Made‑to‑Order Columns & Pricing Information
This is a custom, made‑to‑order column.
Columns are manufactured specifically to order
Orders cannot be canceled once placed
Custom columns are non‑returnable