Prep HPLC Column, RP Phenyl, Wide Pore, 10um, 300A. 21.2mm ID x 150mm Length. Cogent Brand. 1 EA.
Additional Information:
Cogent RP Phenyl Wide Pore is MICROSOLV's most popular phenyl stationary phase for reversed-phase HPLC and LC-MS applications involving larger molecules. Built on high-purity silica with a C3-phenyl bonded phase and exhaustive double endcapping, it provides balanced hydrophobic retention combined with strong π-π interactions. This unique selectivity is particularly valuable when C18 or C8 columns do not adequately resolve aromatic, heteroaromatic, or structurally related compounds.
68024-P21-1503M is a preparative HPLC column packed with 10 µm RP Phenyl Wide Pore particles featuring a 300 Å pore size in a 21.2 mm ID x 150 mm format. The large internal diameter provides substantial sample loading capacity, while the 150 mm length delivers increased resolving power for purification of closely related compounds. The 300 Å pore structure improves accessibility for larger molecules, peptides, and complex analytes while maintaining the aromatic selectivity characteristic of RP Phenyl chemistry. Typical operating flow rates are approximately 15–40 mL/min depending on sample load, mobile phase composition, and system capabilities.
This column is well suited for purification of positional isomers, aromatic pharmaceuticals, peptides, tocopherols, flavonoids, polynuclear aromatic compounds, nitro-aromatic compounds, active pharmaceutical ingredients (APIs), natural products, and related aromatic compounds. The scalable RP Phenyl chemistry supports efficient transfer from analytical development to preparative purification workflows.
Key Benefits
RP Phenyl Wide Pore stationary phase
C3-phenyl bonded chemistry
Strong π-π interaction selectivity
300 Å pore size for larger molecules and peptides
High-purity silica support
Fully double endcapped
Reduced silanol activity
Reduced peak tailing
Excellent peak symmetry
Scalable from analytical to preparative chromatography
Typical Applications
Preparative HPLC purification
Fraction collection
Positional isomer purification
Aromatic pharmaceutical purification
Peptide purification
Active pharmaceutical ingredient (API) purification
Tocopherol purification
Flavonoid purification
Natural product isolation
Process development and scale-up
Specifications
Product Type: Preparative HPLC Column
Stationary Phase: RP Phenyl Wide Pore
Chromatography Mode: Reversed Phase
Bonded Phase: C3-Phenyl
Endcapping: Fully Double Endcapped
Particle Size: 10 µm
Pore Size: 300 Å
Column Dimensions: 21.2 mm ID x 150 mm
Length: 150 mm
Typical Flow Rate: 15–40 mL/min
Brand: Cogent
Additional Resources
Special Order Item Information
Important Notes
Designed for purification and fraction collection workflows
Often selected when C18 or C8 phases do not provide adequate selectivity
Strong π-π interactions can improve separation of aromatic compounds
Wide pore design is suitable for larger molecules and peptides
Longer column length provides enhanced resolution for difficult purifications
Requires a preparative HPLC system capable of higher flow rates.