Prep HPLC Column, RP Phenyl, Wide Pore, 10um, 300A. 30mm ID x 100mm Length. Cogent Brand. 1 EA.

Additional Information:

Cogent RP Phenyl Wide Pore is MICROSOLV's most popular phenyl stationary phase for reversed-phase HPLC and LC-MS applications involving larger molecules. Built on high-purity silica with a C3-phenyl bonded phase and exhaustive double endcapping, it combines hydrophobic retention with strong π-π interactions to provide enhanced selectivity for aromatic and structurally related compounds that may not separate sufficiently on traditional C18 or C8 columns.

68024-P30-1003M is a preparative HPLC column packed with 10 µm RP Phenyl Wide Pore particles featuring a 300 Å pore size in a 30 mm ID x 100 mm format. The large internal diameter provides exceptionally high sample loading capacity, while the 100 mm length offers an excellent balance between throughput and chromatographic efficiency. The 300 Å pore structure improves accessibility for larger molecules and peptides, while the 10 µm particle size supports high flow rates with lower operating backpressure. Typical operating flow rates are approximately 30–80 mL/min depending on sample load, mobile phase composition, and system capabilities.

This column is particularly effective for purification of larger aromatic compounds, peptides, positional isomers, active pharmaceutical ingredients (APIs), tocopherols, flavonoids, natural products, and related compounds. The RP Phenyl chemistry provides a scalable pathway from analytical method development to large-scale preparative purification.

Key Benefits

  • RP Phenyl Wide Pore stationary phase

  • C3-phenyl bonded chemistry

  • Strong π-π interaction selectivity

  • 300 Å pore size for larger molecules and peptides

  • High-purity silica support

  • Fully double endcapped

  • Reduced silanol activity

  • Reduced peak tailing

  • Excellent peak symmetry

  • Scalable from analytical to preparative chromatography

Typical Applications

  • Preparative HPLC purification

  • Fraction collection

  • Peptide purification

  • Positional isomer purification

  • Aromatic pharmaceutical purification

  • Active pharmaceutical ingredient (API) purification

  • Tocopherol purification

  • Flavonoid purification

  • Natural product isolation

  • Process development and scale-up

Specifications

  • Product Type: Preparative HPLC Column

  • Stationary Phase: RP Phenyl Wide Pore

  • Chromatography Mode: Reversed Phase

  • Bonded Phase: C3-Phenyl

  • Endcapping: Fully Double Endcapped

  • Particle Size: 10 µm

  • Pore Size: 300 Å

  • Column Dimensions: 30 mm ID x 100 mm

  • Length: 100 mm

  • Typical Flow Rate: 30–80 mL/min

  • Brand: Cogent

Additional Resources

Special Order Item Information

Important Notes

  • Designed for purification and fraction collection workflows

  • Often selected when C18 or C8 phases do not provide adequate selectivity

  • Wide pore design improves accessibility for larger molecules and peptides

  • Large diameter format provides exceptionally high sample loading capacity

  • Requires a preparative HPLC system capable of higher flow rates and fraction collection


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