Process HPLC Column, RP Phenyl, 10um, 100A. 50mm ID x 100mm Length. Cogent Brand. 1 EA.
Additional Information:
Cogent RP Phenyl is MICROSOLV's most popular phenyl stationary phase for reversed-phase HPLC and LC-MS applications. Built on high-purity silica with a C3-phenyl bonded phase and exhaustive double endcapping, it combines hydrophobic retention with strong π-π interactions to provide enhanced selectivity for aromatic and structurally related compounds that may not separate sufficiently on traditional C18 or C8 columns.
68024-P50-100 is a process-scale HPLC column packed with 10 µm RP Phenyl particles featuring a 100 Å pore size in a 50 mm ID x 100 mm format. The large internal diameter provides very high sample loading capacity for process-scale purification, while the 100 mm length balances throughput and chromatographic efficiency. The 10 µm particle size supports high flow rates with lower operating backpressure, making this column suitable for production environments, large-scale purification, and process development. Typical operating flow rates are approximately 80–200 mL/min depending on sample load, mobile phase composition, and system capabilities.
This column is particularly effective for purification of positional isomers, aromatic pharmaceuticals, tocopherols, flavonoids, polynuclear aromatic compounds, nitro-aromatic compounds, active pharmaceutical ingredients (APIs), natural products, and related aromatic compounds. The RP Phenyl chemistry provides a scalable pathway from analytical method development through preparative purification and process-scale production.
Key Benefits
RP Phenyl stationary phase with C3-phenyl bonded chemistry
Strong π-π interaction selectivity
High-purity silica support
Fully double endcapped
Reduced silanol activity
Reduced peak tailing
Excellent peak symmetry
Very high loading capacity
Ideal for aromatic and phenyl-containing compounds
Scalable from analytical to process chromatography
Typical Applications
Process HPLC purification
Large-scale fraction collection
Positional isomer purification
Aromatic pharmaceutical purification
Active pharmaceutical ingredient (API) purification
Tocopherol purification
Flavonoid purification
Polynuclear aromatic compound purification
Natural product isolation
Production-scale chromatography
Specifications
Product Type: Process HPLC Column
Stationary Phase: RP Phenyl
Chromatography Mode: Reversed Phase
Bonded Phase: C3-Phenyl
Endcapping: Fully Double Endcapped
Particle Size: 10 µm
Pore Size: 100 Å
Column Dimensions: 50 mm ID x 100 mm
Length: 100 mm
Typical Flow Rate: 80–200 mL/min
Brand: Cogent
Additional Resources
Special Order Item Information
Important Notes
Designed for process-scale purification and production workflows
Often selected when C18 or C8 phases do not provide adequate selectivity
Strong π-π interactions can improve separation of aromatic compounds
Large diameter format supports high sample loading and throughput
Requires a specialized process HPLC system capable of high flow rates and large-volume fraction collection