Semi Prep HPLC Column, RP Phenyl, 10um, 100A. 10mm ID x 100mm Length. Cogent Brand. 1 EA.
Additional Information:
Cogent RP Phenyl is MICROSOLV's most popular phenyl stationary phase for reversed-phase HPLC and LC-MS applications. Built on high-purity silica with a C3-phenyl bonded phase and exhaustive double endcapping, it combines hydrophobic retention with strong π-π interactions to provide enhanced selectivity for aromatic and structurally related compounds that may not separate sufficiently on traditional C18 or C8 columns.
68024-SP100 is a semi-preparative HPLC column packed with 10 µm RP Phenyl particles featuring a 100 Å pore size in a 10 mm ID x 100 mm format. The larger internal diameter provides increased sample loading capacity compared to analytical columns, while the 100 mm length balances throughput and chromatographic efficiency. The 10 µm particle size supports higher flow rates with lower operating backpressure, making this column well suited for purification, method scale-up, and semi-preparative separations. Typical operating flow rates are approximately 4–12 mL/min depending on sample load, mobile phase composition, and system capabilities.
This column is particularly effective for purification of positional isomers, aromatic pharmaceuticals, tocopherols, flavonoids, polynuclear aromatic compounds, nitro-aromatic compounds, active pharmaceutical ingredients (APIs), natural products, and related aromatic compounds. The RP Phenyl chemistry provides a scalable pathway from analytical method development to semi-preparative purification workflows.
Key Benefits
RP Phenyl stationary phase with C3-phenyl bonded chemistry
Strong π-π interaction selectivity
High-purity silica support
Fully double endcapped
Reduced silanol activity
Reduced peak tailing
Excellent peak symmetry
Increased loading capacity versus analytical columns
Ideal for aromatic and phenyl-containing compounds
Scalable from analytical to semi-preparative chromatography
Typical Applications
Semi-preparative HPLC purification
Fraction collection
Positional isomer purification
Aromatic pharmaceutical purification
Active pharmaceutical ingredient (API) purification
Tocopherol purification
Flavonoid purification
Polynuclear aromatic compound purification
Natural product isolation
Method scale-up
Specifications
Product Type: Semi-Preparative HPLC Column
Stationary Phase: RP Phenyl
Chromatography Mode: Reversed Phase
Bonded Phase: C3-Phenyl
Endcapping: Fully Double Endcapped
Particle Size: 10 µm
Pore Size: 100 Å
Column Dimensions: 10 mm ID x 100 mm
Length: 100 mm
Typical Flow Rate: 4–12 mL/min
Brand: Cogent
Additional Resources
Special Order Item Information
Important Notes
Designed for purification and fraction collection workflows
Often selected when C18 or C8 phases do not provide adequate selectivity
Strong π-π interactions can improve separation of aromatic compounds
Increased loading capacity compared to analytical columns
Requires a semi-preparative HPLC system capable of higher flow rates and larger injection volumes