Semi Prep HPLC Column, RP Phenyl, 10um, 100A. 10mm ID x 50mm Length. Cogent Brand. 1 EA.
Additional Information:
Cogent RP Phenyl is MICROSOLV's most popular phenyl stationary phase for reversed-phase HPLC and LC-MS applications. Built on high-purity silica with a C3-phenyl bonded phase and exhaustive double endcapping, it combines hydrophobic retention with strong π-π interactions to provide enhanced selectivity for aromatic and structurally related compounds that may not separate sufficiently on traditional C18 or C8 columns.
68024-SP50 is a semi-preparative HPLC column packed with 10 µm RP Phenyl particles featuring a 100 Å pore size in a 10 mm ID x 50 mm format. The larger internal diameter provides increased sample loading capacity compared to analytical columns, while the shorter column length is optimized for rapid purification cycles, method development, and high-throughput separations. The 10 µm particle size supports higher flow rates with lower operating backpressure. Typical operating flow rates are approximately 4–12 mL/min depending on sample load, mobile phase composition, and system capabilities.
This column is particularly effective for purification of positional isomers, aromatic pharmaceuticals, tocopherols, flavonoids, polynuclear aromatic compounds, nitro-aromatic compounds, active pharmaceutical ingredients (APIs), natural products, and related aromatic compounds. The RP Phenyl chemistry provides a scalable pathway from analytical method development to semi-preparative purification workflows.
Key Benefits
RP Phenyl stationary phase with C3-phenyl bonded chemistry
Strong π-π interaction selectivity
High-purity silica support
Fully double endcapped
Reduced silanol activity
Reduced peak tailing
Excellent peak symmetry
Increased loading capacity versus analytical columns
Ideal for aromatic and phenyl-containing compounds
Scalable from analytical to semi-preparative chromatography
Typical Applications
Semi-preparative HPLC purification
Fraction collection
Positional isomer purification
Aromatic pharmaceutical purification
Active pharmaceutical ingredient (API) purification
Tocopherol purification
Flavonoid purification
Polynuclear aromatic compound purification
Natural product isolation
Method scale-up
Specifications
Product Type: Semi-Preparative HPLC Column
Stationary Phase: RP Phenyl
Chromatography Mode: Reversed Phase
Bonded Phase: C3-Phenyl
Endcapping: Fully Double Endcapped
Particle Size: 10 µm
Pore Size: 100 Å
Column Dimensions: 10 mm ID x 50 mm
Length: 50 mm
Typical Flow Rate: 4–12 mL/min
Brand: Cogent
Additional Resources
Special Order Item Information
Important Notes
Designed for purification and fraction collection workflows
Short column length supports rapid purification cycles and high-throughput separations
Often selected when C18 or C8 phases do not provide adequate selectivity
Increased loading capacity compared to analytical columns
Requires a semi-preparative HPLC system capable of higher flow rates and larger injection volumes