Catalog Number - 58846-06-005

58846-06-005 ARE‑Applied Research Mobile Phase Inlet Filters are high‑performance, biocompatible solvent filtration devices engineered for HPLC, UHPLC, and LC‑MS mobile phase delivery systems, providing very high flow capacity, maximum solvent recovery, and critical instrument protection.

These filters utilize a “Last Drop” flat‑profile design, enabling nearly complete withdrawal of mobile phase from reservoir bottles—an essential advantage for high‑flow systems, long analytical runs, overnight sequences, and expensive solvent applications.

Each filter is constructed with a 5 µm PTFE filter element and an inert PEEK / PTFE wetted flow path, ensuring excellent chemical compatibility, low extractables, and stable performance in demanding analytical environments.

✅ See pack of 2 options for smaller quantity purchasing and flexibility

“Last Drop” Design – Maximum Solvent Utilization

• Flat bottom‑draw filter geometry

• Designed to sit at the lowest point in the bottle

• Draws solvent to near‑empty conditions

• Reduces waste and prevents pump starvation

✅ Ideal for high‑flow applications and long analytical sequences

✅ Improves lab efficiency and solvent cost control

5 µm PTFE Element – High Flow / High Capacity Filtration

• Filters particles ≥ 5 µm

• Protects:

  • Pump seals and check valves

  • Injection systems

  • HPLC columns and detectors

• Larger pore size provides:

  • Very high flow rates

  • Low flow restriction

  • Extended service life

✅ Ideal for high‑flow systems or pre‑filtered mobile phases

Visual Inspection Advantage – White Filter Element

• White PTFE surface enhances visibility of trapped particles

• Enables quick evaluation of contamination buildup

• Helps determine optimal replacement timing

✅ Supports proactive maintenance and consistent performance

PEEK / PTFE Flow Path – High Purity Performance

• Wetted components made from:

  • PEEK (polyether ether ketone)

  • PTFE (inert fluoropolymer)

• Ensures:

  • Chemical inertness

  • Minimal extractables and leachables

  • Broad solvent compatibility

✅ Suitable for LC‑MS, analytical, and biocompatible workflows

1/8" Connector with ETFE Ferrule – High‑Flow Integration

• Integrated 1/8" tubing connector

• Includes ETFE ferrule for non‑flanged tubing

• Provides secure, leak‑free connection

• No additional fittings required

✅ Ideal for higher flow rate systems and larger tubing configurations

Performance Advantages – Modern HPLC Operation

Compared to finer‑pore inlet filters:

• Lower flow resistance for improved throughput

• Reduced likelihood of clogging in high‑flow applications

• Stable solvent delivery at elevated flow rates

• Extended intervals between filter replacements

✅ Aligns with best practices for high‑efficiency chromatography systems

System Compatibility & Use

Designed for use with:

• HPLC / UHPLC mobile phase systems

• LC‑MS solvent delivery setups

• Low‑pressure tubing systems (1/8")

• Standard mobile phase reservoir bottles

✅ Installs directly into mobile phase bottles for inline filtration

Typical Applications

• High‑flow HPLC mobile phase filtration

• LC‑MS solvent protection

• Pre‑filtered solvent systems

• Routine analytical workflows

• Long‑duration and unattended runs

• Integrated into original equipment manufacturer (OEM) product designs

Important Usage Notes

• Designed for low‑pressure systems only

• Ensure proper tubing installation with ferrule

• Inspect regularly for particulate buildup

• Replace filter when flow decreases or restriction increases