Catalog Number - 58846-09-005

58846-09-005 ARE‑Applied Research Mobile Phase Inlet Filters are high‑capacity, biocompatible solvent filtration devices engineered for HPLC, UHPLC, and LC‑MS mobile phase delivery systems, offering maximum solvent recovery, ultra‑low flow restriction, and dependable protection of critical instrument components.

These filters utilize a “Last Drop” flat bottom‑draw design, allowing nearly complete withdrawal of solvent from reservoir bottles—an essential advantage for high‑flow systems, long analytical runs, and bulk solvent workflows where minimizing waste and avoiding interruptions is critical.

Each unit is constructed with a 10 µm PTFE filter element and an inert PEEK / PTFE wetted flow path, delivering excellent chemical compatibility, minimal extractables, and extended service life in demanding analytical environments.

✅ See pack of 2 options for smaller quantity purchasing and ordering flexibility

“Last Drop” Design – Maximum Solvent Utilization

• Wide 22 mm flat bottom‑draw geometry

• Designed to sit at the lowest point in the bottle

• Draws solvent to near‑empty conditions

• Minimizes waste and prevents pump starvation

✅ Ideal for bulk solvent handling, high‑throughput labs, and long sequences

✅ Improves efficiency and solvent cost control

10 µm PTFE Element – Ultra‑High Flow Capacity

• Filters particles ≥ 10 µm

• Protects:

  • Pump seals and check valves

  • Injection systems

  • HPLC columns and detectors

• Larger pore size provides:

  • Maximum flow capacity

  • Minimal restriction / lowest backpressure

  • Longest service life in the filter series

✅ Ideal for pre‑filtered solvents and high‑flow applications

Visual Inspection Advantage – White Filter Element

• White PTFE surface enhances visibility of trapped particles

• Enables quick contamination assessment

• Helps determine optimal replacement timing

✅ Supports proactive maintenance and consistent system performance

PEEK / PTFE Flow Path – High Purity Performance

• Wetted components made from:

  • PEEK (polyether ether ketone)

  • PTFE (inert fluoropolymer)

• Provides:

  • Chemical inertness

  • Minimal extractables and leachables

  • Broad solvent compatibility

✅ Suitable for LC‑MS, analytical, and biocompatible workflows

1/8" Connector with ETFE Ferrule – High‑Flow Integration

• Integrated 1/8" tubing connector

• Includes ETFE ferrule for non‑flanged tubing

• Provides secure, leak‑free connection

• No additional fittings required

✅ Ideal for higher flow rate systems and larger tubing configurations

Performance Advantages – High‑Flow Chromatography Systems

Compared to smaller pore filters:

• Lowest restriction for maximum throughput

• Reduced clogging risk

• Improved flow stability at high flow rates

• Extended maintenance intervals

✅ Aligns with best practices for high‑efficiency chromatography systems

System Compatibility & Use

Designed for use with:

• HPLC / UHPLC mobile phase systems

• LC‑MS solvent delivery setups

• Low‑pressure tubing systems (1/8")

• Standard mobile phase reservoir bottles

✅ Installs directly into mobile phase bottles for inline filtration

Typical Applications

• High‑flow HPLC mobile phase filtration

• Bulk solvent preparation and delivery

• LC‑MS solvent protection

• Pre‑filtered solvent workflows

• Routine analytical laboratory operations

• Long‑duration and unattended runs

• Integrated into original equipment manufacturer (OEM) product designs

Important Usage Notes

• Designed for low‑pressure systems only

• Ensure proper tubing installation with included ferrule

• Inspect filter element regularly for buildup

• Replace when flow performance declines