Formamide Compatible Nylon Syringe Filters - Tech Information
February 18, 2020
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Date: 18-February-2020   Last Updated: 25-FEBRUARY-2026

Overview

Amide solvents such as formamide, dimethylformamide (DMF), and acetamide are widely used in life‑science workflows, nucleic acid preparations, peptide chemistry, and various analytical procedures. Choosing a syringe filter that maintains integrity when exposed to these aggressive solvents is essential for both safety and chromatographic accuracy.

MICROSOLV’s AQ™ Brand Nylon Syringe Filters are engineered for broad chemical compatibility and have been verified to withstand long‑term exposure to these high‑polarity solvents without membrane degradation, leaching, or performance loss.

This makes them an excellent choice for labs that routinely process amide‑based solutions.


Compatibility With Amide‑Based Solvents

Laboratories working with amide solvents should ensure that the filter membrane and housing materials are stable and extractable‑free. AQ™ nylon devices maintain structural and chemical resilience when used with:

Formamide

  • Fully compatible
  • No swelling or structural compromise
  • Suitable for high‑purity sample filtration

Dimethylformamide (DMF)

  • Fully compatible
  • Membrane maintains porosity and strength
  • Excellent for sample preparation and method development

Acetamide

  • Fully compatible
  • No known adverse membrane interactions
  • Recommended for organic and biochemical workflows

This broad compatibility makes AQ™ nylon a versatile choice for demanding analytical applications.


Why AQ™ Nylon Filters Perform Well

AQ™ Brand Nylon Syringe Filters are known for:

  • High chemical resistance to polar aprotic solvents
  • Low extractables due to advanced membrane washing and manufacturing controls
  • Mechanical durability even under pressure
  • Consistent pore structure, ensuring reproducible filtration
  • Compatibility across a wide range of organic and aqueous solvents

This makes them ideal for researchers needing reliable filtration without risking solvent‑induced contamination or loss of analyte.


Applications Involving Formamide & Related Solvents

AQ™ nylon filters are commonly used in workflows such as:

  • DNA/RNA denaturation processes using formamide
  • Peptide synthesis cleanup involving DMF
  • Protein or ligand solubilization with amide solvents
  • Polar organic extraction and preparation
  • Analytical and preparative chromatography filtration steps

Their solvent tolerance ensures stability and purity during all these applications.


Ordering Information

For ordering details, catalog numbers, technical specifications, and product images for AQ™ Brand Nylon Syringe Filters: Click HERE for ordering information and pictures of AQ brand of syringe filters.
 

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