Which Column Coupler do You Recommend for Pairing HPLC Columns with Guard Columns- Tech Information
May 9, 2023
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Date: 9-MAY-2023   Last Updaed: 8-NOVEMBER-2025

The ARE-Applied Research™ brand of column couplers are used to connect the flow of two HPLC columns or a guard column and an analytical column directly in series.


Below is our recommended selection chart to match your flow rate and a suggested union-column coupler (ID).  The ID of the coupler should be determined based on your application, where the faster the flow, the larger the bore (ID) is needed.


 
Flow rate
(milliliters / minute)
Through Hole
(mm)
Through Hole (inch) Column Coupler
Cat. No.
up to 0.5 0.13 0.005 47450-01
≤1.0 0.18 0.007 47450-02
1.0 - 2.0 0.25 0.010 47450-03
≥2.0 0.50 0.020 47450-04
 
 

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