Syringe Filters, 25mm, Cellulose Acetate, 0.45um Pore Size. Orange Polypropylene, AQ Brand. 100/PK.
Additional Info:
The 58045-CA25 AQ™ Syringe Filters are pharmaceutical-grade membrane filters designed for HPLC sample preparation and dissolution testing in regulated laboratory environments. Featuring a 0.45 µm Cellulose Acetate (CA) membrane, these filters provide consistent performance, low extractables, and reliable chromatography—ideal for high-throughput analytical workflows.
Cellulose Acetate membranes are naturally hydrophilic and surfactant-free, eliminating risk of extractable contaminants common in other hydrophilic filters. With very low protein binding, they are well suited for biological and aqueous samples where maximum analyte recovery is critical.
✅ Critical Compliance Advantage (No Flush Required)
These filters are validated and certified to meet key regulatory requirements:
US FDA CFR Title 21, Part 211.92 – minimum fiber release
USP <788> – particulate matter in injectables
USP “Sterile Water for Injection”
Resulting benefits:
✅ No initial flushing required
✅ No 200 µL discard required
✅ Improves sample recovery and workflow efficiency
✅ Reduces risk of failed methods
Performance & Design
The 0.45 µm pore size is optimized for sample clarification and prefiltration, providing high flow rates and reduced clogging.
The 25 mm format supports larger sample volumes, making it ideal for routine and high-throughput workflows.
The CA membrane offers excellent performance for aqueous solutions and biological samples, particularly where low protein binding and clean baselines are required.
The orange housing ensures easy identification, and each pack includes a Certificate of Analysis for traceability.
Key Features
0.45 µm Cellulose Acetate Membrane (Pharma Grade)
Ideal for aqueous and biological samples
Surfactant-free for low extractables
✅ No Initial Flush Required (Validated)
No 200 µL discard required
Low Protein Binding
Maximizes sample recovery
Ideal for biological applications
Hydrophilic Membrane
Suitable for aqueous solutions
No pre-wetting required
High Throughput (25 mm)
Handles larger sample volumes
Reduces clogging
Regulatory Compliance
Meets FDA CFR 21 (211.92)
Complies with USP <788>
Color-Coded (Orange)
Identifies 0.45 µm CA filters
Typical Applications
HPLC & UHPLC Sample Preparation – aqueous sample clarification
Biological Samples – protein / biomolecule filtration
Dissolution Testing – pharmaceutical QC
Buffer & Media Filtration – clean, low-binding performance
Routine Analytical Workflows – reproducible results
Specifications
Membrane Material: Cellulose Acetate (CA)
Pore Size: 0.45 µm
Diameter: 25 mm
Housing: Polypropylene (PP)
Color Code: Orange
Protein Binding: Low
Hydrophilicity: Hydrophilic
Extractables: None detectable (no flush required)
Sterilization: Autoclave or EO
Compliance: FDA CFR 21, USP <788>
Pack Size: 100/PK
Brand: AQ™
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