Syringe Filters, 25mm, Cellulose Acetate, 0.45um Pore Size. Orange Polypropylene, AQ Brand. 1000/CS.
Additional Info:
The 58045-CA25-K AQ™ Syringe Filters are pharmaceutical-grade, high-throughput membrane filters designed for HPLC sample preparation and dissolution testing in regulated laboratory environments. Featuring a 0.45 µm Cellulose Acetate (CA) membrane, these filters provide reliable performance, low extractables, and consistent chromatography for routine and large-scale workflows.
Cellulose Acetate membranes are naturally hydrophilic and surfactant-free, eliminating extractable contaminants common in many hydrophilic filters. With very low protein binding, they are ideal for biological and aqueous samples where maximum recovery is required.
✅ Critical Compliance Advantage (No Flush Required)
Validated to meet key regulatory standards:
US FDA CFR Title 21, Part 211.92 – minimum fiber release
USP <788> – particulate matter in injectables
USP “Sterile Water for Injection”
Benefits:
✅ No initial flushing required
✅ No 200 µL discard required
✅ Improves recovery and efficiency
✅ Reduces risk of failed methods
Performance & Design
The 0.45 µm pore size is optimized for sample clarification and prefiltration, providing high flow rates and reduced clogging.
The 25 mm format supports higher sample volumes, making it ideal for high-throughput QC, analytical, and production environments.
CA membranes excel in aqueous and biological applications, where low protein binding and clean baselines are critical.
The orange housing provides easy identification, and each case includes a Certificate of Analysis for traceability.
Key Features
0.45 µm Cellulose Acetate Membrane (Pharma Grade)
Ideal for aqueous and biological samples
Surfactant-free, low extractables
✅ No Initial Flush Required (Validated)
No 200 µL discard required
Low Protein Binding
Maximizes analyte recovery
Hydrophilic Membrane
No pre-wetting required
High Throughput (25 mm)
Handles larger sample volumes
Bulk Packaging (1000/Case)
Reduces cost per analysis
Ideal for high-volume labs
Regulatory Compliance
FDA CFR 21 (211.92), USP <788>
Color-Coded (Orange)
Identifies CA filters
Typical Applications
HPLC & UHPLC Sample Preparation – aqueous sample clarification
Biological Samples – protein / biomolecule filtration
Dissolution Testing – pharmaceutical QC
Buffers & Media Filtration – clean, low-binding performance
High-Throughput Laboratories – consistent results
Specifications
Membrane Material: Cellulose Acetate (CA)
Pore Size: 0.45 µm
Diameter: 25 mm
Housing: Polypropylene (PP)
Color Code: Orange
Protein Binding: Low
Hydrophilicity: Hydrophilic
Extractables: None detectable (no flush required)
Sterilization: Autoclave or EO
Compliance: FDA CFR 21, USP <788>
Pack Size: 1000/Case
Brand: AQ™
Resources & Ordering Options
Order Cellulose Acetate syringe filters, 0.45 µm, 25 mm – 100/pack quantity
Purchase Cellulose Acetate syringe filters, 0.45 µm, 25 mm – 50/pack quantity