Catalog Number - 58045-CA25-A

The 58045-CA25-A AQ™ Syringe Filters are pharmaceutical-grade membrane filters designed for HPLC sample preparation and dissolution testing in regulated laboratory environments. Featuring a 0.45 µm Cellulose Acetate (CA) membrane, these filters provide reliable performance, low extractables, and consistent chromatography for routine and high-throughput workflows.

Cellulose Acetate membranes are naturally hydrophilic and surfactant-free, eliminating extractable contaminants found in many hydrophilic filters. With very low protein binding, they are ideal for biological and aqueous samples requiring maximum recovery.

✅ Critical Compliance Advantage (No Flush Required)

Validated to meet key regulatory standards:

• US FDA CFR Title 21, Part 211.92 – minimum fiber release

• USP <788> – particulate matter in injectables

• USP “Sterile Water for Injection”

Benefits:

• ✅ No initial flushing required

• ✅ No 200 µL discard required

• ✅ Improves recovery and efficiency

• ✅ Reduces risk of failed methods

Performance & Design

The 0.45 µm pore size is optimized for sample clarification and prefiltration, providing high flow rates and reduced clogging.

The 25 mm format supports larger sample volumes, making it ideal for routine and high-throughput workflows.

CA membranes are well suited for aqueous solutions and biological samples, where low protein binding and clean baselines are essential.

The orange housing allows quick identification, and each pack includes a Certificate of Analysis.

Key Features

0.45 µm Cellulose Acetate Membrane (Pharma Grade)

• Ideal for aqueous and biological samples

• Surfactant-free, low extractables

✅ No Initial Flush Required (Validated)

• No 200 µL discard required

Low Protein Binding

• Maximizes analyte recovery

Hydrophilic Membrane

• No pre-wetting required

High Throughput (25 mm)

• Handles larger sample volumes

Regulatory Compliance

• FDA CFR 21 (211.92), USP <788>

Color-Coded (Orange)

• Identifies CA filters

Typical Applications

• HPLC & UHPLC Sample Preparation – aqueous sample clarification

• Biological Samples – protein / biomolecule filtration

• Dissolution Testing – pharmaceutical QC

• Buffers & Media – clean filtration

• Routine Analytical Workflows

Specifications

• Membrane Material: Cellulose Acetate (CA)

• Pore Size: 0.45 µm

• Diameter: 25 mm

• Housing: Polypropylene (PP)

• Color Code: Orange

• Protein Binding: Low

• Hydrophilicity: Hydrophilic

• Extractables: None detectable (no flush required)

• Sterilization: Autoclave or EO

• Compliance: FDA CFR 21, USP <788>

• Pack Size: 50/PK

• Brand: AQ™

Resources & Ordering Options

• Order Cellulose Acetate syringe filters, 0.45 µm, 25 mm – 100/pack quantity

• Purchase Cellulose Acetate syringe filters, 0.45 µm, 25 mm – 1000/case quantity