Metabolomics Development Kit, 4.6x150. 1 Cogent Diamond Hydride™ & 1 Cogent Bidentate C18™. Cogent TYPE-C Brand. 1 PK.
Additional Info:
The 43000‑15P Metabolomics Development Kit provides an economical, application‑focused pairing of two widely used TYPE‑C™ silica hydride HPLC columns for metabolomics and broader small‑molecule workflows. This kit includes one Cogent Diamond Hydride™ HPLC Column and one Cogent Bidentate C18™ HPLC Column, allowing direct comparison of HILIC‑style and reversed‑phase separations using matched column geometry on standard analytical LC systems.
Both columns are manufactured with Cogent TYPE‑C™ silica hydride technology, delivering fast equilibration, reproducible retention, and robust performance across a wide range of analytical methods.
Kit Composition
This development kit contains two analytical HPLC columns:
Shared specifications for both columns:
Internal Diameter: 4.6 mm
Length: 150 mm
Particle Size: 4 µm
Pore Size: 100 Å
Stationary Phase Platform: Cogent TYPE‑C™ silica hydride
Using identical dimensions and particle architecture allows meaningful method‑development comparisons without introducing variability from column geometry or chromatography mode.
Application Focus: Metabolomics & LC Method Development
The two stationary phases in this kit provide complementary selectivity across polar and non‑polar chemical space:
Cogent Diamond Hydride™
HILIC‑style retention on a stable silica‑hydride surface
Strong retention for highly polar and ionic metabolites
Rapid equilibration and excellent method reproducibility
Cogent Bidentate C18™
Reversed‑phase retention with dual‑point C18 bonding
Enhanced stability versus conventional bonded C18 phases
Effective for less polar and hydrophobic metabolites
Together, these columns enable broad metabolite coverage using a consistent TYPE‑C™ surface chemistry.
Why Choose the 4.6 mm × 150 mm Format
The 4.6 mm ID × 150 mm length configuration is frequently selected for robust analytical method development on standard LC platforms:
Higher resolving power than 100 mm formats
Excellent peak capacity for complex samples
Standard analytical flow rates compatible with most LC systems
Well suited for UV, ELSD, CAD, and LC‑MS workflows
This format offers an effective balance between resolution, instrument compatibility, and operational simplicity.
System Requirements and Flow Rates
Typical flow range (4.6 mm ID): ~1.0–1.5 mL/min
Compatible with standard analytical HPLC and LC systems
Requires no specialized low‑flow or UHPLC‑only hardware
Flow conditions should be optimized based on mobile‑phase composition, temperature, and system pressure limits.