Catalog Number - 58846-06-002

58846-06-002 ARE‑Applied Research Mobile Phase Inlet Filters are high‑performance, biocompatible solvent filtration devices engineered for HPLC, UHPLC, and LC‑MS mobile phase delivery systems, providing very high flow capacity, maximum solvent recovery, and critical instrument protection.

These filters utilize a “Last Drop” flat‑profile design, enabling nearly complete withdrawal of mobile phase from reservoir bottles. This is especially valuable for high‑flow systems, long analytical runs, overnight sequences, and costly solvent systems.

Each filter is built with a 5 µm PTFE filter element and an inert PEEK / PTFE wetted flow path, ensuring excellent chemical compatibility, low extractables, and consistent performance across demanding analytical workflows.

✅ Explore bulk quantity options for lab standardization and cost efficiency

“Last Drop” Design – Maximum Solvent Utilization

• Flat bottom‑draw filter geometry

• Designed to sit at the lowest point in the bottle

• Draws solvent to near‑dry conditions

• Reduces solvent waste and prevents pump starvation

✅ Ideal for high‑throughput labs and high‑flow applications

✅ Improves workflow efficiency and run continuity

5 µm PTFE Element – High Flow / High Capacity Filtration

• Removes particles ≥ 5 µm

• Protects:

  • Pump seals and check valves

  • Injection systems

  • Columns and detectors

• Larger pore size provides:

  • Very high flow rates

  • Low backpressure contribution

  • Longer service life

✅ Ideal for high‑flow systems and pre‑filtered solvents

Visual Inspection Advantage – White Filter Element

• White PTFE surface allows easy visibility of trapped particles

• Enables fast inspection of contamination

• Helps determine when replacement is required

✅ Supports proactive maintenance and consistent system performance

PEEK / PTFE Flow Path – High Purity Performance

• Wetted materials:

  • PEEK (polyether ether ketone)

  • PTFE (inert fluoropolymer)

• Provides:

  • Chemical inertness

  • Low extractables and leachables

  • Broad solvent compatibility

✅ Suitable for LC‑MS, analytical, and biocompatible workflows

1/8" Connector with ETFE Ferrule – High‑Flow Integration

• Integrated 1/8" tubing connector

• Includes ETFE ferrule for non‑flanged tubing

• Ensures secure, leak‑free connection

• No additional fittings required

✅ Ideal for higher flow rate systems and larger tubing configurations

Performance Advantages – Modern HPLC Operation

Compared to finer‑pore inlet filters:

• Lower flow restriction for improved throughput

• Reduced likelihood of clogging in high‑flow applications

• Stable solvent delivery under demanding conditions

• Extended service intervals

✅ Aligns with best practices for high‑efficiency chromatography systems

System Compatibility & Use

Designed for use with:

• HPLC / UHPLC mobile phase systems

• LC‑MS solvent delivery setups

• Low‑pressure tubing systems (1/8")

• Standard mobile phase reservoir bottles

✅ Installs directly into mobile phase bottles for inline filtration

Typical Applications

• High‑flow HPLC mobile phase filtration

• LC‑MS solvent protection

• Pre‑filtered solvent systems

• Routine analytical workflows

• Long‑duration and unattended runs

• Integrated into original equipment manufacturer (OEM) product designs

Important Usage Notes

• Designed for low‑pressure systems only

• Ensure proper tubing installation with ferrule

• Inspect for particulate buildup regularly

• Replace filter when flow decreases or restriction increases