Catalog Number - 58846-E-08

58846-E-08 ARE‑Applied Research Mobile Phase Inlet Filter is a biocompatible, all‑PTFE economy filtration solution engineered for HPLC, UHPLC, and LC‑MS mobile phase delivery systems, providing maximum solvent recovery, ultra‑low flow restriction, and reliable system protection.

This filter incorporates a “Last Drop” flat bottom‑draw design, enabling nearly complete withdrawal of mobile phase from reservoir bottles—ideal for high‑volume workflows, long analytical runs, and bulk solvent applications where minimizing waste is critical.

Constructed entirely from PTFE, this filter delivers exceptional chemical compatibility, minimal extractables, and long service life, making it suitable for both routine and sensitive analytical applications.

✅ Explore pack size options for flexible purchasing and lab inventory control

“Last Drop” Design – Maximum Solvent Utilization

• 22 mm flat filter geometry

• Sits at the lowest point in the reservoir bottle

• Draws solvent to near‑empty conditions

• Minimizes waste and prevents pump starvation

✅ Ideal for bulk solvent handling and extended analytical runs

✅ Improves efficiency and solvent cost management

10 µm PTFE Element – Ultra‑High Flow Capacity

• Filters particulates ≥ 10 µm

• Protects:

  • Pump seals and check valves

  • Injection systems

  • HPLC columns and detectors

• Larger pore size provides:

  • Maximum flow capacity

  • Minimal flow restriction

  • Longest service life among PTFE options

✅ Ideal for high‑flow systems and pre‑filtered solvents

All‑PTFE Construction – Maximum Chemical Compatibility

• Fully PTFE wetted surfaces

• No mixed‑material flow path

• Highly inert and resistant to aggressive solvents

✅ Ideal for LC‑MS, pharmaceutical, and biocompatible workflows

Visual Inspection Advantage – White Filter Element

• White PTFE surface enhances visibility of trapped particles

• Enables rapid contamination assessment

• Helps determine optimal replacement timing

✅ Supports proactive maintenance and consistent system performance

Tubing Compatibility – Flexible Integration

• Designed for 1/8" low‑pressure tubing systems

• Requires user‑configured tubing attachment

• Compatible with standard HPLC solvent setups

✅ Ideal for custom or simplified tubing configurations

Economy Design – Cost‑Effective Performance

• Simplified construction without integrated connector fittings

• Lower cost compared to advanced inlet filter designs

• Maintains:

  • High filtration efficiency

  • Maximum solvent recovery

  • Reliable system protection

✅ Ideal for budget‑conscious labs and high‑volume workflows

Performance Advantages – High‑Flow Chromatography Systems

Compared to smaller pore filters:

• Lowest restriction for maximum throughput

• Reduced clogging risk

• Stable solvent delivery at high flow rates

• Extended service intervals

✅ Aligns with best practices for high‑efficiency chromatography systems

System Compatibility & Use

Designed for use with:

• HPLC / UHPLC mobile phase systems

• LC‑MS solvent delivery setups

• 1/8" low‑pressure tubing configurations

• Standard mobile phase reservoir bottles

✅ Installs directly into mobile phase bottles for inline filtration

Typical Applications

• High‑flow HPLC mobile phase filtration

• Bulk solvent preparation and handling

• LC‑MS solvent protection

• Pre‑filtered solvent workflows

• Routine analytical and QC laboratories

• Long‑duration and unattended runs

• Integrated into original equipment manufacturer (OEM) product designs

Important Usage Notes

• Designed for low‑pressure systems only

• Requires compatible 1/8" tubing setup

• Ensure secure tubing connection during installation

• Inspect filter regularly and replace as needed