Catalog Number - 58846-E-02

58846-E-02 ARE‑Applied Research Mobile Phase Inlet Filter is a cost‑effective, biocompatible, all‑PTFE filtration solution designed for HPLC, UHPLC, and LC‑MS mobile phase delivery systems, offering high filtration efficiency and maximum solvent utilization.

This economy configuration features a simplified all‑PTFE design without integrated connectors, making it ideal for labs that prefer custom tubing configurations or budget‑focused purchasing while maintaining high performance.

With its “Last Drop” flat bottom‑draw profile, this filter enables nearly complete use of solvent within the reservoir bottle—helping reduce waste and maintain uninterrupted operation.

“Last Drop” Design – Maximum Solvent Utilization

• 22 mm flat filter geometry

• Positioned at the bottom of the bottle

• Draws solvent to near‑empty conditions

• Reduces waste and prevents pump starvation

✅ Ideal for cost‑sensitive labs running long or high‑volume methods

✅ Improves solvent efficiency and operational continuity

2.5 µm PTFE Element – Biocompatible Filtration

• Removes particles ≥ 2.5 µm (noted: some specs reference ≥2 µm removal range)

• Protects:

  • Pump seals and valves

  • Injectors

  • Columns and detectors

• PTFE media provides:

  • Broad chemical compatibility

  • Biocompatibility

  • Low adsorption and extractables

✅ Suitable for LC‑MS, pharmaceutical, and general HPLC workflows

All‑PTFE Construction – Maximum Chemical Compatibility

• Fully PTFE (Teflon®‑type) wetted surfaces

• No metal or polymer variability in flow path

• Extremely inert and resistant to aggressive solvents

✅ Ideal for high‑purity and sensitive applications

Visual Inspection Advantage – White Filter Element

• White PTFE surface enables easy visibility of trapped particles

• Allows quick assessment of contamination

• Supports timely replacement for optimal performance

✅ Enhances maintenance efficiency and system uptime

Tubing Compatibility – Flexible Integration

• Designed for use with 1/8" low‑pressure tubing systems

• Requires user‑configured tubing attachment

• Suitable for simple or custom solvent setups

✅ Ideal for labs that prefer flexible or standardized tubing assemblies

Performance Advantages – Economy Meets Functionality

Compared to integrated connector designs:

• Lower cost per unit

• Simplified construction

• Full compatibility with standard HPLC setups

Maintains key benefits:

• Maximum solvent utilization

• Effective particulate removal

• High flow capacity

✅ Provides economical access to high‑performance inlet filtration

System Compatibility & Use

Designed for use with:

• HPLC / UHPLC mobile phase systems

• LC‑MS solvent delivery setups

• 1/8" low‑pressure tubing configurations

• Standard mobile phase reservoir bottles

✅ Installs directly into mobile phase bottles for inline filtration

Typical Applications

• HPLC mobile phase filtration (economy setups)

• LC‑MS solvent protection

• Budget‑conscious laboratories

• General analytical workflows

• High‑volume solvent usage environments

• Integrated into original equipment manufacturer (OEM) product designs

Important Usage Notes

• Designed for low‑pressure systems only

• Requires 1/8" tubing compatibility

• Ensure secure tubing connection during installation

• Inspect element regularly and replace as needed