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PTFE (polytetrafluoroethylene) tubing—commonly referred to as Teflon® tubing—is the most widely used and most economical polymeric tubing for low‑pressure chromatography and general laboratory applications. PTFE tubing is commonly installed before the injector, after the detector, at mobile‑phase inlets, and on “to‑waste” lines in HPLC systems, as well as in low‑pressure LC and auxiliary laboratory workflows where chemical inertness is required.

All MicroSolv™ PTFE tubing is manufactured from virgin PTFE resin and is chemically inert, making it suitable for routine solvent handling and low‑pressure fluid transfer.


Why Choose PTFE Tubing

PTFE tubing is selected for its broad chemical resistance, temperature stability, and cost effectiveness in non‑pressurized fluid paths.

Key characteristics include:

  • Extruded from virgin PTFE fluoropolymer resin

  • Excellent chemical inertness for a wide range of solvents

  • Low coefficient of friction

  • Negligible moisture absorption

  • Stable electrical and physical properties across wide temperature ranges

  • Most economical option among polymeric tubing materials

PTFE tubing is widely used across analytical, research, and general laboratory environments.


Micro‑Porosity & Solvent Considerations

Important consideration: All PTFE tubing has a coherent, low‑density fibrous structure that contains micro‑pores within the tubing wall. These micro‑pores allow rapid gas exchange with the surrounding environment.

This characteristic is especially important when:

  • Using degassed solvents

  • Handling oxygen‑sensitive mobile phases

  • Maintaining strict solvent composition is critical

For applications where gas permeation is undesirable, alternative materials such as PFA or FEP tubing may be more appropriate.


Temperature & Pressure Characteristics

PTFE tubing is intended for low‑pressure applications and offers a very wide usable temperature range:

  • Maximum temperature: 260 °C (500 °F)

  • Minimum temperature: –240 °C (–400 °F)

Operating PTFE within recommended pressure limits ensures long‑term performance in solvent handling lines.


Dimensional Tolerances

PTFE tubing is manufactured to tolerances appropriate for low‑pressure chromatography applications:

  • 1/16″ OD tubing: ± 0.10 mm

  • 1/8″ OD tubing: ± 0.20 mm

These tolerances reflect the material structure of PTFE and are suitable for auxiliary fluid paths and solvent transfer.


Purity & Regulatory Considerations

All MICROSOLV™ PTFE tubing:

  • Is extruded from virgin PTFE

  • Contains no plasticizers or performance‑altering additives

  • Meets FDA food‑contact compliance per 21 CFR 177.1550

  • Complies with EU Regulation No. 10/2011, where applicable

Color is used only for external identification and does not affect the internal fluid path.


Typical Applications

PTFE tubing is commonly used for:

  • HPLC mobile‑phase inlet lines

  • Post‑detector waste lines

  • Low‑pressure solvent transfer

  • General laboratory fluid handling

  • Auxiliary, non‑pressurized connections


Specifications

👉 View polymeric tubing specifications and available sizes


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