Protect Your HPLC Columns While in Use | Extend System Service Life
Guard columns are an excellent way to protect your HPLC columns during use. They should always match the stationary phase of your analytical or prep column. Matching phases will slightly extend your column length without altering selectivity. Using a different phase may trap some analytes, which is not considered effective column protection.
Guard columns adsorb various chemical entities and undissolved particles before they reach your main column. These particles can permanently adsorb to the analytical column, altering its character and selectivity. When you notice changes in peak shape or retention time, it’s time to replace the guard column.
The holders for Cogent guard systems are listed on this page, and the actual guard cartridges are available with their respective stationary phases.
NOTE: Our technical support team strongly recommends that the Cogent column filter, included with each column, be used with all HPLC columns whenever possible. Click HERE for details.
