What is the Difference Between a Luer Lock and a Luer Slip Connector or Syringe - FAQ
September 27, 2012
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Date: 27-SEPTEMBER-2012 Last Updated: 3-NOVEMBER-2025
More Information Chrom Syringes
When working with syringes and accessories like syringe filters and tubing connectors, it's important to understand the difference between Luer Lock and Luer Slip connectors, as each serves a distinct purpose in laboratory and clinical settings.
Luer Slip Connector
- A Luer Slip connection allows the syringe or device to simply slide onto the tip of another compatible component (e.g., a syringe filter).
- To ensure a snug fit, apply firm forward pressure and give the device a quarter turn during attachment.
- While this connection is generally secure for most applications, it does not lock in place and may disconnect under high pressure or vigorous handling.
Luer Lock Connector
- A Luer Lock connection features a threaded locking mechanism that securely fastens the device to the syringe.
- The “wings” or threads on the syringe filter screw into the syringe’s Luer Lock fitting, creating a fixed, leak-resistant seal.
- This design is ideal for applications involving high back pressure or where a secure, stable connection is critical for safety and performance.
Key Differences at a Glance
| Feature | Luer Slip | Luer Lock |
|---|---|---|
| Connection Type | Push-on with optional twist | Screw-on with locking parts |
| Security | Moderate | High |
| Best For | General use | High-pressure or critical systems |
| Risk of Disconnection | Possible under pressure | Minimal |
More Information Chrom Syringes