Semi Prep Guard Column Cartridge, RP PFP, 10um, 100A. 10mm ID x 10mm Length. Cogent Brand. 5/PK.

Additional Info:

68022-SP-PG1 Cogent RP PFP™ Guard Column Cartridge is designed to protect semi‑prep HPLC columns from particulates and strongly retained contaminants that can reduce column performance and lifespan. Packed with 10 µm Cogent RP PFP™ material, this guard cartridge matches the selectivity of the analytical and semi‑prep PFP columns it supports.

This column utilizes a fully double end‑capped surface bonded via a four‑carbon linker to a benzene ring substituted with five fluorine atoms, using high purity 100 Å silica. This chemistry provides consistent retention behavior and ensures compatibility with RP PFP analytical methods.

Each cartridge is packed in a durable stainless steel tube with stainless steel frits, providing strength and performance under semi‑prep and higher flow conditions.

10 mm ID × 10 mm Length – Semi‑Prep Column Protection

This guard column cartridge is optimized for use with 10 mm ID semi‑prep columns, offering effective protection without significantly impacting chromatographic performance.

  • Protects against particulates and strongly retained contaminants

  • Extends the life of semi‑prep columns

  • Maintains consistent chromatographic selectivity

✅ Recommended for all semi‑prep workflows using 10 mm ID RP PFP columns

Flow Rate & System Requirements (10 mm ID, 10 µm)

⚠️ Requires semi‑preparative or preparative HPLC system capability

  • Typical flow rate range: ~3.0 – 6.0 mL/min

  • Very low backpressure due to 10 µm particle size

  • Designed for high-flow semi‑prep applications

  • Compatible with preparative detectors and fraction collection systems

✅ Required Hardware: Use with a 10 mm ID guard column holder (see Guard Column Holder product page for compatibility and specifications)

Why Use RP PFP Guard Columns

Column Protection

  • Prevents contamination from particulates and sample matrix

  • Reduces irreversible adsorption on main column

Maintains Selectivity

  • Matches RP PFP column chemistry

  • Ensures consistent analytical results

Improves Workflow Efficiency

  • Reduces downtime and column replacement frequency

  • Extends usable column life

Cogent RP PFP™ Guard Cartridge Advantages

Matched Chemistry

  • Same selectivity as RP PFP columns

Durable Construction

  • Stainless steel body and frits for high flow operation

Low Backpressure (10 µm Particles)

  • Ideal for higher flow semi‑prep methods

Typical Applications

  • Semi‑prep HPLC workflows

  • Method development and scale‑up

  • Halogenated compound separations

  • Aromatic compound purification

  • Pharmaceutical preparative analysis

Important Usage Notes

  • Designed for use with 10 mm ID prep column holders

  • Packed and shipped in reversed‑phase solvents

  • Requires semi‑prep or preparative HPLC system

  • Replace guard cartridges regularly to maintain performance

Made‑to‑Order Columns & Pricing Information

This is a custom, made‑to‑order column.

  • Columns are manufactured specifically to order

  • Orders cannot be canceled once placed

  • Custom columns are non‑returnable

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