Click HERE for Frequently Asked Questions about TYPE-C Silica columns.

Click HERE for Application Notes.

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We are always ready to lend any support we can. Our experienced scientists and professionals are ready to assist you with any technical support questions. Every question is considered a good question and we will work with you on a solution as fast as possible.

  • Call us: 8:30AM – 6:00PM EST 1-732-380-8900 and hit 0#

  • Fax to us: 1-910-769-9435

  • Email Technical Support

RP or ANP  |  Weak cation exchange | Undecanoic acid - Dual mode possible.

These columns have an 11 carbon, aliphatic linker with a terminal, carboxylic acid group (Undecanoic Acid) bonded to the silica hydride surface. This phase is very unique as it has weak cation exchange (wcx) properties in addition to those of aqueous normal phase (ANP) mode. A dual mode is possible with some mobile phase conditions.

The carboxylic acid group contributes some additional selectivity to the phase. When the mobile phase is above pH 5.9 the acid group becomes 90% negatively charged and at pH 6.9 it becomes 99% charged and may act as a cation exchanger. Below pH 4.9, the group does not have significant ion exchange properties and should be used primarily for ANP. Recommendation: to use the cation exchange function with this column, use a mobile phase around pH 6 or higher if possible.

The Cogent UDA column is a good choice for LCMS and precise methods are easily developed even with complex sample matrices as very little desalting is required.

  • Click HERE to view specifications.

  • Click HERE for more information "About TYPE-C columns".

  • Click HERE for "How to use Cogent UDA HPLC columns.

NOTE: Our technical support team strongly recommends that the Cogent column filter, included with each column, be used with all HPLC columns whenever possible. Click HERE for details.

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