Catalog Number - 58846-02

58846-02 ARE‑Applied Research Mobile Phase Inlet Filter is a high‑performance, biocompatible solvent filtration device designed for HPLC, UHPLC, and LC‑MS mobile phase delivery systems, offering excellent filtration efficiency, solvent utilization, and system protection.

This filter features a “Last Drop” flat‑profile design, allowing nearly complete use of solvents from reservoir bottles, making it ideal for long sequences, overnight runs, and high‑value mobile phases.

Constructed with a 2.5 µm PTFE filter element and an inert PEEK flow path, this design provides high throughput, low extractables, and excellent compatibility with sensitive analytical workflows, including bio‑applications.

✅ Explore additional pack sizes and purchasing options to support lab efficiency and inventory planning

“Last Drop” Design – Maximum Solvent Utilization

• Wide 22 mm flat filter geometry

• Sits at the lowest point in the bottle

• Draws solvent to near‑empty conditions

• Minimizes waste and reduces system interruptions

✅ Ideal for long HPLC runs and high‑throughput workflows

✅ Improves solvent efficiency and run consistency

2.5 µm PTFE Element – Biocompatible Filtration

• Filters particles ≥ 2.5 µm

• Protects:

  • Pump seals and valves

  • HPLC columns

  • Detector and system components

• PTFE media offers:

  • Broad chemical compatibility

  • Biocompatibility for sensitive applications

  • Low extractables and adsorption

✅ Suitable for bioanalytical, pharmaceutical, and LC‑MS workflows

Visual Inspection Advantage – White PTFE Element

• White filter media enhances visibility of trapped particles

• Easy visual confirmation of contamination buildup

• Simplifies maintenance and replacement decisions

✅ Supports proactive system maintenance and uptime

PEEK Flow Path – High Purity Performance

• All wetted components made from PEEK and PTFE

• Chemically inert and resistant to aggressive solvents

• Maintains solvent integrity and analytical reproducibility

✅ Ideal for high‑purity chromatography applications

1/16" Connector with ETFE Ferrule – Secure Tubing Integration

• Integrated 1/16" tubing connector

• Includes ETFE ferrule for secure fit

• Compatible with non‑flanged low‑pressure tubing

• Leak‑free connection without additional fittings

✅ Enables reliable and easy tubing installation

Performance Advantages – Modern Chromatography Systems

Compared to traditional inlet filters:

• Maximizes usable solvent volume

• Reduces risk of air entering pump systems

• Improves flow stability near empty conditions

• Enables longer unattended operation

Advanced inlet filtration supports:

• Longer instrument life

• Improved chromatographic reproducibility

• Reduced maintenance frequency

✅ Aligns with best practices for HPLC system protection

System Compatibility & Use

Designed for use with:

• HPLC / UHPLC mobile phase systems

• LC‑MS solvent delivery systems

• Low‑pressure tubing configurations

• Standard mobile phase reservoir bottles

✅ Installs directly into mobile phase bottles for inline filtration

Typical Applications

• HPLC mobile phase filtration

• LC‑MS solvent protection

• Biocompatible and pharmaceutical workflows

• High‑throughput analytical laboratories

• Long‑duration analytical runs

• Integrated into original equipment manufacturer (OEM) product designs

Important Usage Notes

• Designed for low‑pressure systems only

• Ensure proper tubing insertion with ferrule for sealing

• Inspect filter element regularly for buildup

• Replace element as needed to maintain flow performance