HPLC Tubing Adapters | OD & ID Transitions - MICROSOLV Technology Corporation

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HPLC Tubing Adapters | OD & ID Transitions

Learn the difference between Waters and standard fittings.

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HPLC tubing adapters are used to connect tubing with different outer diameters (OD), inner diameters (ID), or connection interfaces within liquid chromatography systems. These adapters provide a practical way to modify or extend fluidic paths without replacing entire tubing assemblies or system components.

This category includes low‑, medium‑, and high‑pressure tubing adapters, primarily manufactured in PEEK, suitable for adapting flow paths in both analytical and system‑level HPLC configurations.

Purpose & Function

Tubing adapters are commonly used to:

Connect tubing with different OD or ID dimensions
Transition between connection types (e.g., compression to compression)
Modify system layouts during method development or reconfiguration
Integrate components from different manufacturers
Support incremental system upgrades without full replumbing

Adapters are essential in environments where flexibility and compatibility are required.

Connection Types & Configurations

Tubing adapters in this category are available in multiple configurations, including:

Female‑to‑male adapters
Female‑to‑female adapters
Reducer styles for OD or ID transitions

These options allow precise adaptation of tubing and fittings while maintaining secure, low‑dead‑volume connections.

Materials & Pressure Considerations

Adapters are primarily offered under the ARE‑Applied Research™ brand and are manufactured from PEEK, providing:

Broad chemical compatibility with common HPLC solvents
Suitability for low‑ and medium‑pressure applications
Bio‑inert and metal‑free flow paths where required

Adapter selection should consider operating pressure, solvent exposure, and system location.

Applications & Use Cases

HPLC tubing adapters are commonly used for:

System plumbing and modification
Method development and prototyping
OEM fluidic sub‑assemblies
Connecting legacy systems to newer components
Laboratory environments supporting multiple instrument configurations

Availability & Custom Options

A variety of standard adapter configurations are available for immediate use. Additional sizes, connection styles, and low‑pressure polypropylene adapters may be available for specialized applications.

👉 Contact Customer Service for assistance with non‑standard configurations or OEM requirements.

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Product Ordering Information

Catalog#
Description
Pricing

49302-08
Union, Connector, low pressure, 1.0 mm / 0.040 inch through hole with 10-32 to 1/4-28 reducing screw threads. Carbon PEEK Endure. Use with 1/16 tubing. ARE-Applied Research brand. Bulk Price.

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49302-08-005
Union, Connector, low pressure, 1.0 mm / 0.040 inch through hole with 10-32 to 1/4-28 reducing screw threads. Carbon PEEK Endure. Use with 1/16 tubing. ARE-Applied Research brand. 5/PK.

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49302-08-010
Union, Connector, low pressure, 1.0 mm / 0.040 inch through hole with 10-32 to 1/4-28 reducing screw threads. Carbon PEEK Endure. Use with 1/16 tubing. ARE-Applied Research brand. 10/PK.

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47451-12
Adapter, for use with low to medium pressure HPLC. 1/4-28 female to female Luer connection, 1.3 mm / 0.051 bore size. PEEK. ARE-Applied Research brand. Bulk Price.

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47451-12-005
Adapter, for use with low to medium pressure HPLC. 1/4-28 female to female Luer connection, 1.3 mm / 0.051 bore size. PEEK. ARE-Applied Research brand. 5/PK.

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47451-12-010
Adapter, for use with low to medium pressure HPLC. 1/4-28 female to female Luer connection, 1.3 mm / 0.051 bore size. PEEK. ARE-Applied Research brand. 10/PK.

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47451-32
Adapter, for use with low to medium pressure HPLC. 10-32 female to female Luer connection, 1.3 mm / 0.051 bore size. ARE-Applied Research brand. Bulk Price.

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47451-32-005
Adapter, for use with low to medium pressure HPLC. 10-32 female to female Luer connection, 1.3 mm / 0.051 bore size. PEEK. ARE-Applied Research brand. 5/PK.

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47451-32-010
Adapter, for use with low to medium pressure HPLC. 10-32 female to female Luer connection, 1.3 mm / 0.051 bore size. PEEK. ARE-Applied Research brand. 10/PK.

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47451-01
Adapter, for use with low to medium pressure HPLC. 1/4-28 female to 10/32 male connection, 0.40 mm / 0.016 bore size. PEEK. ARE-Applied Research brand. Bulk Price.

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47451-01-005
Adapter, for use with low to medium pressure HPLC. 1/4-28 female to 10-32 male connection, 0.40 mm / 0.016 bore size. PEEK. ARE-Applied Research brand. 5/PK.

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47451-01-010
Adapter, for use with low to medium pressure HPLC. 1/4-28 female to 10-32 male connection, 0.40 mm / 0.016 bore size. PEEK. ARE-Applied Research brand. 10/PK.

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47451-02
Adapter, for use with low to medium pressure HPLC. 1/4-28 female to male luer connection, 1.3 mm / 0.051 bore size. PEEK. ARE-Applied Research brand. Bulk Price.

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47451-02-005
Adapter, for use with low to medium pressure HPLC. 1/4-28 female to male luer connection, 1.3 mm / 0.051 bore size. PEEK. ARE-Applied Research brand. 5/PK.

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47451-02-010
Adapter, for use with low to medium pressure HPLC. 1/4-28 female to male luer connection, 1.3 mm / 0.051 bore size. PEEK. ARE-Applied Research brand. 10/PK.

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47451-21
Adapter, for use with low to medium pressure HPLC. 1/4-28 female to M6 male connection, 0.40 mm / 0.016 bore size. PEEK. ARE-Applied Research brand. Bulk Price.

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47451-21-005
Adapter, for use with low to medium pressure HPLC. 1/4-28 female to M6 male connection, 0.40 mm / 0.016 bore size. PEEK. ARE-Applied Research brand. 5/PK.

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47451-21-010
Adapter, for use with low to medium pressure HPLC. 1/4-28 female to M6 male connection, 0.40 mm / 0.016 bore size. PEEK. ARE-Applied Research brand. 10/PK.

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47451-41
Adapter, for use with low to medium pressure HPLC. 10-32 female to 1/4-28 male connection, 0.40 mm / 0.016 bore size. PEEK. ARE-Applied Research brand. Bulk Price.

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47451-41-005
Adapter, for use with low to medium pressure HPLC. 10-32 female to 1/4-28 male connection, 0.40 mm / 0.016 bore size. PEEK. ARE-Applied Research brand. 5/PK.

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47451-41-010
Adapter, for use with low to medium pressure HPLC. 10-32 female to 1/4-28 male connection, 0.40 mm / 0.016 bore size. PEEK. ARE-Applied Research brand. 10/PK.

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47451-42
Adapter, for use with low to medium pressure HPLC. 10-32 female to male luer connection, 1.3 mm / 0.051 bore size. PEEK. ARE-Applied Research brand. Bulk Price.

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47451-42-005
Adapter, for use with low to medium pressure HPLC. 10-32 female to male luer connection, 1.3 mm / 0.051 bore size. PEEK. ARE-Applied Research brand. 5/PK.

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47451-42-010
Adapter, for use with low to medium pressure HPLC. 10-32 female to male luer connection, 1.3 mm / 0.051 bore size. PEEK. ARE-Applied Research brand. 10/PK.

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47451-51
Adapter, for use with low to medium pressure HPLC. 10-32 female to M6 male connection, 0.40 mm / 0.016 bore size. PEEK. ARE-Applied Research brand. Bulk Price.

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47451-51-005
Adapter, for use with low to medium pressure HPLC. 10-32 female to M6 male connection, 0.40 mm / 0.016 bore size. PEEK. ARE-Applied Research brand. 5/PK.

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47451-51-010
Adapter, for use with low to medium pressure HPLC. 10-32 female to M6 male connection, 0.40 mm / 0.016 bore size. PEEK. ARE-Applied Research brand. 10/PK.

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47451-04
Adapter, for use with luer lock devices, 1/4-28 flat bottom female threaded adapter to male luer fitting. PEEK. ARE-Applied Research brand. Bulk Price.

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47451-04-005
Adapter, for use with Luer Lock devices, 1/4-28 flat bottom female threaded adapter to male luer fitting. PEEK. ARE-Applied Research brand. 5/PK.

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47451-04-010
Adapter, for use with Luer Lock devices, 1/4-28 flat bottom female threaded adapter to male luer fitting. PEEK. ARE-Applied Research brand. 10/PK.

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47451-W-01
Adapter, for use with low to medium pressure HPLC. Waters female to 10-32 male connection, 0.40 mm / 0.016 bore size. Natural PEEK. ARE-Applied Research brand. Bulk Price.

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47451-W-01-005
Adapter, for use with low to medium pressure HPLC. Waters female to 10-32 male connection, 0.40 mm / 0.016 bore size. Natural PEEK. ARE-Applied Research brand. 5/PK.

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47451-W-01-010
Adapter, for use with low to medium pressure HPLC. Waters female to 10-32 male connection, 0.40 mm / 0.016 bore size. Natural PEEK. ARE-Applied Research brand. 10/PK.

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47451-W-01K
Adapter, for use with low to medium pressure HPLC. Waters female to 10-32 male connection, 0.40 mm / 0.016 bore size. Black PEEK. ARE-Applied Research brand. Bulk Price.

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47451-W-01K-005
Adapter, for use with low to medium pressure HPLC. Waters female to 10-32 male connection, 0.40 mm / 0.016 bore size. Black PEEK. ARE-Applied Research brand. 5/PK.

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47451-W-01K-010
Adapter, for use with low to medium pressure HPLC. Waters female to 10-32 male connection, 0.40 mm / 0.016 bore size. Black PEEK. ARE-Applied Research brand. 10/PK.

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47451-W-41
Adapter, for use with low to medium pressure HPLC. Waters female to 1/4-28 male connection, 0.40 mm / 0.016 bore size. PEEK. ARE-Applied Research brand. Bulk Price.

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47451-W-41-005
Adapter, for use with low to medium pressure HPLC. Waters female to 1/4-28 male connection, 0.40 mm / 0.016 bore size. PEEK. ARE-Applied Research brand. 5/PK.

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47451-W-41-010
Adapter, for use with low to medium pressure HPLC. Waters female to 1/4-28 male connection, 0.40 mm / 0.016 bore size. PEEK. ARE-Applied Research brand. 10/PK.

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47451-W-61
Adapter, for use with low to medium pressure HPLC. Waters female to Waters male connection, 0.40 mm / 0.016 bore size. PEEK. ARE-Applied Research brand. Bulk Price.

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47451-W-61-005
Adapter, for use with low to medium pressure HPLC. Waters female to Waters male connection, 0.40 mm / 0.016 bore size. PEEK. ARE-Applied Research brand. 5/PK.

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47451-W-61-010
Adapter, for use with low to medium pressure HPLC. Waters female to Waters male connection, 0.40 mm / 0.016 bore size. PEEK. ARE-Applied Research brand. 10/PK.

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47452-02
Adapter, for use with low pressure. 1/4-28 male rotating connection to barbed connection for 3/32 inch tubing. Polypropylene. ARE-Applied Research brand. Bulk Price.

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47452-02-010
Adapter, for use with low pressure. 1/4-28 male rotating connection to barbed connection for 3/32 inch tubing. Polypropylene. ARE-Applied Research brand. 10/PK.

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47452-03
Adapter, for use with low pressure. Barbed connection for 3/32 inch tubing to M6 male connection. Polypropylene. ARE-Applied Research brand. Bulk Price.

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47452-03-010
Adapter, for use with low pressure. Barbed connection for 3/32 inch tubing to M6 male connection. Polypropylene. ARE-Applied Research brand. 10/PK.

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47452-05
Adapter, for use with low pressure. Barbed connection for 1/16 inch tubing to 1/8 inch tubing. Polypropylene. ARE-Applied Research brand. Bulk Price.

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47452-05-010
Adapter, for use with low pressure. Barbed connection for 1/16 inch tubing to 1/8 inch tubing. Polypropylene. ARE-Applied Research brand. 10/PK.

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47452-07
Adapter, for use with low pressure HPLC. 3/32 inch barbed connection. Polypropylene. ARE-Applied Research brand. Bulk Price.

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47452-07-010
Adapter, for use with low pressure HPLC. 3/32 inch barbed connection. Polypropylene. ARE-Applied Research brand. 10/PK.

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47452-08
Adapter, for use with low pressure. Barbed connection for 3/32 inch tubing to 1/16 inch tubing. Polypropylene. ARE-Applied Research brand. Bulk Price.

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47452-08-010
Adapter, for use with low pressure. Barbed connection for 3/32 inch tubing to 1/16 inch tubing. Polypropylene. ARE-Applied Research brand. 10/PK.

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47452-09
Adapter, for use with low pressure. Barbed connection for 3/32 inch to 1/8 inch tubing. Polypropylene. ARE-Applied Research brand. Bulk Price.

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47452-09-010
Adapter, for use with low pressure. Barbed connection for 3/32 inch to 1/8 inch tubing. Polypropylene. ARE-Applied Research brand. 10/PK.

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47452-10
Adapter, for use with low pressure. Female luer lock to barbed connection for 1/16 inch tubing. Polypropylene. ARE-Applied Research brand. Bulk Price.

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47452-10-010
Adapter, for use with low pressure. Female luer lock to barbed connection for 1/16 inch tubing. Polypropylene. ARE-Applied Research brand. 10/PK.

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47452-11
Adapter, for use with low pressure HPLC. Female luer to 1/4-28 male connection. Polypropylene. ARE-Applied Research brand. Bulk Price.

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47452-11-010
Adapter, for use with low pressure HPLC. Female luer to 1/4-28 male connection. Polypropylene. ARE-Applied Research brand. 10/PK.

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47452-12
Adapter, for use with low pressure. Female luer lock to barbed connection for 1/8 inch tubing. Polypropylene. ARE-Applied Research brand. Bulk Price.

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47452-12-010
Adapter, for use with low pressure. Female luer lock to barbed connection for 1/8 inch tubing. Polypropylene. ARE-Applied Research brand. 10/PK.

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47452-13
Adapter, for use with low pressure HPLC. Female luer to 10/32 male connection. Polypropylene. ARE-Applied Research brand. Bulk Price.

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47452-13-010
Adapter, for use with low pressure HPLC. Female luer to 10/32 male connection. Polypropylene. ARE-Applied Research brand. 10/PK.

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47452-14
Adapter, for use with low pressure. Female luer lock to barbed connection for 3/32 inch tubing. Polypropylene. ARE-Applied Research brand. Bulk Price.

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47452-14-010
Adapter, for use with low pressure. Female luer lock to barbed connection for 3/32 inch tubing. Polypropylene. ARE-Applied Research brand. 10/PK.

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47452-15
Adapter, for use with low pressure. Female luer lock to female luer lock. Polypropylene. ARE-Applied Research brand. Bulk Price.

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47452-15-010
Adapter, for use with low pressure. Female luer lock to female luer lock. Polypropylene. ARE-Applied Research brand. 10/PK.

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47452-31
Adapter, for use with low pressure. Male luer to 1/4-28 male connection. Polypropylene. ARE-Applied Research brand. Bulk Price.

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47452-31-010
Adapter, for use with low pressure. Male luer to 1/4-28 male connection. Polypropylene. ARE-Applied Research brand. 10/PK.

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47452-32
Adapter, for use with low pressure. Male luer to barbed connection for 1/8 inch tubing. Polypropylene. ARE-Applied Research brand. Bulk Price.

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47452-32-010
Adapter, for use with low pressure. Male luer to barbed connection for 1/8 inch tubing. Polypropylene. ARE-Applied Research brand. 10/PK.

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47452-33
Adapter, for use with low pressure. Male luer to 10/32 male connection. Polypropylene. ARE-Applied Research brand. Bulk Price.

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47452-33-010
Adapter, for use with low pressure. Male luer to 10/32 male connection. Polypropylene. ARE-Applied Research brand. 10/PK.

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47452-34
Adapter, for use with low pressure HPLC. Male luer to 3/32 inch barbed connection. Polypropylene. ARE-Applied Research brand. Bulk Price.

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47452-34-010
Adapter, for use with low pressure HPLC. Male luer to 3/32 inch barbed connection. Polypropylene. ARE-Applied Research brand. 10/PK.

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47453-01
Adapter, for use with low pressure HPLC. Female luer thread style with 5/16 inch Hex to 1/4-28 UNF bottom sealing thread. White nylon ARE-Applied Research brand. Bulk Price.

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47453-01-010
Adapter, for use with low pressure HPLC. Female luer thread style with 5/16 inch Hex to 1/4-28 UNF bottom sealing thread. White nylon ARE-Applied Research brand. 10/PK.

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49029-02
Check Valve, luer, pocket for 0.122-inch (3.1 mm) OD tubing to male locking luer. Clear-Transparent MABS and Blue-Transparent SAN with Silicone Diaphragm. Bulk Price.

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49029-02-010
Check Valve, luer, pocket for 0.122-inch (3.1 mm) OD tubing to male locking luer. Clear-Transparent MABS and Blue-Transparent SAN with Silicone Diaphragm. 10/PK.

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HPLC Tubing Adapters | OD & ID Transitions