All‑PEEK HPLC column sets are designed for laboratories that pack their own bioinert chromatography columns and require full control over column materials, frit selection, and packing conditions. This category includes extruded PEEK column hardware assemblies suitable for analytical and preparative HPLC applications where metal‑free flow paths and chemical inertness are required.
These column sets are used by column‑packing professionals and advanced users who build custom columns in‑house for method development, bioanalytical work, and specialized separations.
Why Choose All‑PEEK Column Hardware
All‑PEEK column hardware is manufactured from extruded PEEK tubing to ensure high dimensional consistency and reproducible packing performance. A controlled amount of graphite (20%) is incorporated into the PEEK formulation to achieve the characteristic black surface finish. No chemical coatings or post‑processing treatments are applied during manufacturing, resulting in a highly biocompatible column interior.
The internal bore of each column develops a smooth, mirror‑like surface through a proprietary extrusion process, rather than surface treatment. This supports consistent packing and reduces unwanted surface interactions in sensitive applications.
Available Column Sizes & Thread Types
All‑PEEK column sets are available in common HPLC dimensions:
2.1 mm ID columns — 1/4‑28 threads
4.6 mm ID columns — 1/2‑20 threads
7.5 mm ID columns — 5/8‑18 threads
Thread selection ensures compatibility with standard packing stations, fitting hardware, and system plumbing.
Frit Options for Packing Control
Column sets support multiple frit materials and porosities to match packing particles and application requirements:
PEEK frits — 5 µm
Titanium (Ti) frits — 0.5 µm, 2 µm, or 5 µm
Frits are selected to retain packing material while maintaining flow stability and biocompatibility. Choice of frit should align with particle size, operating pressure, and method requirements.
Packing Hardware & Slurry Reservoirs
To support successful column packing, this category integrates with:
All‑PEEK packing adapters and end fittings
Slurry reservoir kits for controlled column packing
Replacement packing components for long‑term column maintenance
👉 View All‑PEEK column packing hardware and slurry reservoir options
👉 Guidelines for packing All‑PEEK HPLC columns
Recommended Column Protection
For optimal column performance and longevity, the Cogent® column filter (included with each column set) is strongly recommended for use with all HPLC columns. Proper column filtration helps prevent particulate contamination and protects packed beds from premature fouling.
👉 Learn more about Cogent® column filters and their use
Applications & Use Cases
All‑PEEK column sets are commonly used for:
Bioinert chromatography workflows
In‑house column packing and repacking
Method development and research applications
Pharmaceutical and bioanalytical separations
Custom column dimensions and particle selections
Important Temperature & Pressure Consideration
⚠️ Material caution: Operating All‑PEEK columns and hardware at elevated temperatures significantly reduces pressure stability. Packing pressures and operating conditions should be selected carefully to remain within safe material limits.
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